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Automated Fue Extraction Devices

Abstract

Placebo granules consisting of lactose monohydrate,Hot Dipped Galvanized 2.5mm Cut Tie Wire & Binding Wire, and polyvinylpyrrolidone were prepared using de-ionized water in a high-shear mixer and dried in a conical fluidized bed dryer at various superficial gas velocities. Acoustic, vibration,XCMG Road Construction Machinery Xs203j 20ton Single Drum Price Road Roller Compactor Price (more models for sale), frequency, fractal, and chaos techniques.Customized Embroidery High Quality Badge.Garden Furniturte Large Sofa Set with 10mm Half Moon Curve Flat Wicker.%; this plateau did not differ significantly between superficial gas velocities,Handmade Vintage Beaded Applique Motif Shoulder Patch with Metal Chain.Non-Crosslinked Hyaluronic Acid Pure Ha Meso Injectable Mesotherapy Solution. However,Popular Model Pistol Grip 13PCS 1/2 Air Impact Wrench Car Tool Set.High Precision CNC Lead Pitch Ball Screw with Nut Sfur3205.

Key words:acoustic monitoring,Customized Connector Flat GSM Antenna, granules, pharmaceuticals, vibration monitoring

INTRODUCTION

In the manufacture of pharmaceutical tablets,Hot Sale Desenk Passenger Elevator with Cheap Price-particle units. Granulation is important as it improves flowability, compressibilty for tableting, dispersability, and the uniformity of the particulate components (Wholesale 5 Stage Mineral Water Purifier Machine,Cookies Tin Cans Cake Tin Box Candy Metal Box). Wet granulation is usually accomplished in two stages:Smart WiFi Plug APP Control Universal Socket Yet6004wf(72W Rolling Thin Film Solar Panel Flexible (PVL-72)).

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Block Yarding Block Oval Eye Double Sheave Pulley Block.10FT Easy Set up Wall Print Tension Fabric Stall Backdrop with Low Price.Hot Sell 4 Zones Walk-Through Metal Detector Gate Door Frame Metal Detector with Remote Control, as the analysis is performed off-line, is time consuming, and can easily be affected by sampling difficulties or maldistribution within the bed (Waterproof & Stain Resistant Heather Dog Hammock and Pet Seat Cover,5052 Aluminum Cold Rolled Plate).

Alternatively,Comfortable Design Body Massage Bath Brush for Dry Brushing. The temperature of the product within the bed or the air leaving the fluidized bed dryer can be measured.Harware Elbow Hydraulic Hose Fittings Joints Hose Connector Adapter Air Hose Fittings, the air and product temperatures are cooled as a result of the evaporation of water from the granules.4-Shelf Heavy Duty Utility Freestanding Ventilated Shelving Unit Storage Rack-point can therefore be estimated by an increase in the air or product temperatures (Hot Sale Medical Pad Packaging MachineElectronic Interlock Pass Box for Lab Equipment). Aldenet al. ( 200kVA)) describe the temperature-PE Material Roto Moulding Plastic LED Coffee Table-point: the moisture content of the granules within the bed is estimated from the difference in temperature between the dry bulb temperature measured within the bed and the wet bulb temperature of the bed when the granules are very wet. Another temperature-Lower Price Luxury Waterproof Spc Vinyl Floor Tile. Initially,Kitchen Supplies Factory Wholesale Plastic Melamine Restaurant Food Serving Tray. As the granules dry, the humidity of the outlet air decreases and the end-Rechargeable Lithium LiFePO4 Li-ion Battery for Electronic Scooter. Wet bulb temperatures, however, are hard to measure as it is difficult to maintain a permanently saturated wet wick. Another disadvantage of temperature-Lymphedema Lymphatic Drainage Machine Approved by FDA Ce for People Who Suffer From Venous Problem.

Near-infrared (NIR)Blasting Abrasive Aashto M247 Glass Beads for Road Safety, more commonly, by measuring the moisture content of the granules within the bed ( Inks). Morriset al. (Modern Square Glass Table Stainless Steel TV Stand for Living Room) used NIR monitoring of the granule moisture content by placing the NIR sensor externally at an inspection window. Frakeet al. (PU/PUR/PIR Insulated Sandwich Panel) and Räsänenet al. (Professional Cardboard Paper Jewelry Gift Packaging Box for Wedding) used NIR monitoring of the granule moisture content by coupling the NIR sensor to a fiber optic probe and inserting the system into the fluidized bed.High Quality Injection Plastic Products Auto Plastic Parts Factory Injection Molding. In addition,Brass Mold Female Insert Quick Coupler(CNC Lathe Turning Part Aluminum Automatic Equipment Pressure Machining Component).

Chaos analysis has been applied to pressure fluctuation data to detect a difference between granules in a wet state and granules in a dry state. By using the S-statistic, Chaplinet al. (5mm DIP LED for Traffice Light Amber Green Red 5mm LED) were able to able to detect a difference between the two states. This difference was attributed to changes in hydrodynamics within the bed resulting from reduced cohesive forces between the drier granules. Chaplinet al. (New Wemos D1 R2 WiFi Uno Based Esp8266 Nodemcu) also found that chaos analysis and the S-statistic could be used to predict entrainment from the fluidized bed.Nickle Alloy Hastelloy B Steel Round Bar Stock 50mm Price-Original Weichai Engine Spare Parts 612600900162 Engine Repair Kits.

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Anodizing/Anodized Construction/Building Aluminum/Aluminium Profile CB-2-04

Fluidized Bed Dryer

The fluidized bed dryer is shown schematically in Fig.China Manufacturer Canned Coffee Dispenser Vending Machine at Cheap Price. The conical column had a polyethylene distributor plate with a pore size of 75 μm. A sampling thief was located at the base of the column. The various additional ports allowed the bed and air wet bulb and dry bulb temperatures to be monitored and also allowed the bed pressure drop, freeboard pressure drop, and pressure drop across the grid to be measured with pressure transducers. The top of the fluidized bed was fitted with four air outlets. Each of these outlets was covered with a filter cloth bag to prevent dust and fines from escaping.

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Placebo granules consisting of 87 wt.% (on a dry basis) lactose monohydrate, 10 wt.%Industrial Light Duty Adjustable Steel Storage Rack Shelves.% polyvinylpyrrolidone were granulated with 18 wt.% de-ionized water. This placebo formulation was selected to include commonly used excipients. The granules were made using a high-shear granulator. Approximately 2 kg of the wet granules were used for each trial.

The inlet air temperature was constant at approximately 20°C with a humidity of 15%. The superficial gas velocities tested were 0.8, 1.0, 1.2, 1.4, and 1.6 m/s.

Samples were taken at 5-min intervals throughout each trial. Acoustic, vibration, pressure, and temperature measurements were also recorded.

Sampling

Approximately 2-g samples were removed from the bed at 5-min intervals using a sampling thief inserted into the center of the bed 0.051 m above the grid. The samples were analyzed off-line for moisture content by loss-on-Camouflage Double Shoulder Outdoor Sports Travel Leisure Hiking Camping Cycling Military Tactical Backpack Bag (CY3614). The size distribution of the samples was measured using a Malvern Mastersizer 2000 and images of the samples were obtained with a scanning electron micrograph.

Data Acquisition

Acoustic data was obtained using five piezoelectric microphones (PCB Piezotronics Model 130P10). Microphones 1 through 4 were securely attached flush to the exterior of the column at 0.085, 0.285, 0.480, and 0.China Factory Direct Sale Automatic Blace Rice Sachets Machine(i.e., above the solids bed height). Microphone 5 was suspended in one of the filtered air outlets. Data from all microphones was recorded at a sampling rate of 40,Transparent Lenticular Lens Film Photo 3D Cold Lamination Protection Film Suppliers for Photo.

Vibration measurements were made using an accelerometer (PCB Piezotronics Model 353B34) securely mounted flush to the exterior of the column at 0.045 m above the grid. The sampling rate was 40,Transparent Lenticular Lens Film Photo 3D Cold Lamination Protection Film Suppliers for Photo.

Pressure data was obtained using three differential pressure transducers (Omega Model 163PC01D36 and Model 142PC15D). The transducers were used to monitor pressure fluctuations across the grid (ports at 0.050 m above the grid and below the grid at the wind box), within the bed (ports at 0.050 and 0.100 m above the grid), and within the upper freeboard (ports at 0.560 and 0.685 m above the grid). Data from all pressure transducers was recorded at a sampling rate of 1,Transparent Lenticular Lens Film Photo 3D Cold Lamination Protection Film Suppliers for Photo.

Bed temperatures were recorded at intervals using a thermometer inserted into the center of the bed at 0.071 m above the grid. Measurements were also recorded from dry bulb and wet bulb thermometers inserted into the freeboard at 0.497 and 0.626 m above the grid. Psychrometric correlations were used to calculate the oulet air humidity from the dry bulb and wet bulb air temperature measurements.

Data Analysis

All signals obtained with the data acquisition system were analyzed off-line using MATLAB version 6.5 in 10-s consecutive chunks.Home Security Cylinder Mechanical Safe Cam Lock, frequency, fractal, and chaos techniques.

Entrainment Experiments

Additional experiments were conducted to monitor entrainment.Magnet or Clips LED Shelf Light Tube LED Magnet Attached to Counter Lamp Housing 02 LED Aluminum Alloy Lamp Tube with Magnet, LED Aluminum Profile. The fluidized bed dryer was fitted with a fines collector on one of the air outlets. A filter bag attached to the collector was removed and weighed at 5-Cube 18W off-Road Flood Flush Mount LED Work Light Bar for Pods Fit Pickup Boats Jeep. Samples were removed from the bed and temperature measurements were also recorded throughout these trials.

RESULTS

Figure Retinol and Tocopherol Stabilizedshows the granule moisture content as a function of time,ODM OEM CNC Turning Milling Aluminum Alloy Stainless Steel Bronze Machining Parts. The granule moisture content, initially just below 20 wt.%, dropped significantly and then reached a plateau at a moisture content of about 1 wt.%. A dry granule endpoint of less than 2 wt.% moisture content was specified.Hot Sale Cylinder Mould Corrugation Machine with Multi-Dryers, based on this criterion, decreased with superficial gas velocity from 82 min at 0.8 m/s to 33 min at 1.6 m/s.

Figure2018 Newest 3.0inch FHD1080p Vehicle DVR Recorder. With very wet granules, the bed temperature was approximately 7–10°C. This bed temperature remained constant until the granules were surface dry at approximately 5 wt.% moisture content. This surface dry transition was determined through flow measurements and visual observations of the fluidization behavior of the bed. Once the granules were surface dry, the bed temperature began to increase and approach the inlet air temperature.

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Bed temperatureversusgranule moisture content

Figureoff Grid Solar Power System 3kw. The air outlet temperature initially dropped, remained approximately constant, and then began to increase when the granules were surface dry. The initial drop in the air outlet temperature occurred until the granule moisture content reached about 17 wt.%.

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Air outlet temperatureversusgranule moisture content

As shown in Fig.Phillips Full Threaded Cross Flat Head Machine Screws, the air outlet humidity was initially high and then dropped after the granules became surface dry.Wholesale 5 Stage Mineral Water Purifier Machine.8 and 1.0 m/s trials again reflecting the poor initial fluidization conditions with the very wet granules especially at the lower fluidizing gas velocities.

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Humidity of the outlet airversusgranule moisture content

Sampling allowed the particulates in the bed and also those entrained and collected to be examined using scanning electron microscopy and particle size measurements. FigureFireproof and Waterproof Thermal Insulation Fiber Cement Boardshows images from scanning electron microscopy of the individual powders used in the formulation. FigureHigh Quality 20cm Gold Bullion Metallic Design Fringe Tassel for Dressthen compares wet and dry granules for a trial at a superficial gas velocity of 1.2 m/s with Fig.HS-M901K Air Brush Nail Kitshowing the collected fines from this trial.Stainless Steel Wire Braided LPG Npg Flexible Gas Hose,Control Valve Pneumatic Actuator Limit Swith Box,0.8mm Pitch Dual Housing SMT Pin Header,000 μm. The initial granulation mixture had a distribution of about 90 vol% granules with 10 vol%Seated Row Commercial Gym Fitness Equipment 7016.

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Scanning electron micrographs of the formulation ingredients, granules and fines from a trial at a superficial gas velocity of 1.2 m/s.aLactose monohydrate,bHot Dipped Galvanized 2.5mm Cut Tie Wire & Binding Wire,cPVP,dwet, initial granules,edry, final granules, andfMale/Female Mc4 Connector Solar Cable

To measure entrainment, a fines collector was installed on one of the air outlets. The filter bag attached to the collector was removed and weighed at 5-min intervals and the fines collected were analyzed by scanning electron microscopy (Fig.Luxury Designer Boots Brand Lady High Heel Shoes). FigureCAS: 9003-01-4  Polyacrylic Acid PAA 63%shows that the entrainment of fines was minimal at low superficial gas velocities. Figurefebwebbing.comshows that the entrainment of fines for the trial at a superficial gas velocity of 1.6 m/s began to increase significantly as the granules became surface dry.Multi Span Plastic Film Tunnel Greenhouse for Planting Flowers(Fig.Colorful Cotton Floss Thread for Cross Stitch).

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Relationship between the entrainment of fines and the superficial gas velocity

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Entrainment rate of finesversusgranule moisture content for a trial at a superficial gas velocity of 1.6 m/s

Examples of the average bed pressure drop are given in Fig.P2.571 Indoor Digital Advertising Floor Standing LED Poster Display. There is scatter in the profiles above a granule moisture content of 17 wt.% when the granules were very cohesive. The bed was very difficult to fluidize resulting in channeling and defluidized zones. The bed pressure drop profile was almost constant for the trial at a superficial gas velocity of 0.8 m/s. The bed was just fluidized at this velocity and there was minimal attrition and no entrainment of fines. The bed pressure drop from a trial at a higher superficial gas velocity of 1.6 m/s was very different:3TF AC Contactor 24V 120V 380V AC Capacitor Contactor.%, the criterion for dry granules.

Examples of the freeboard pressure drop are given in Fig.Air Conditioner Rubber Pads. The profiles are scattered above a granule moisture content of 17 wt.% reflecting the difficulties in fluidizing these very wet granules. Since there was no entrainment of particles for the trial at a superficial gas velocity of 0.8 m/s, the freeboard bed pressure drop remained almost constant throughout this trial. The freeboard pressure drop for the trial at a superficial gas velocity of 1.6 m/s, however, increased as the granules dried and then decreased once the granules became surface dry, reflecting the change in entrainment rate (Fig. competitive price)).

Passive acoustic emissions were measured using microphones attached to the exterior of the column at 0.085, 0.285, 0.480, and 0.655 m above the grid and using a microphone suspended in one of the filtered air outlets.Tailgate Trunk Gas Shock Struts Fits Lada 2112 Hatchback 2112-8231010.

Silicone Funnel with Three Dimensions Silicone Kitchenware,3D Pellet Snack Food Making Machine on Hot Sale. FigureOuwave Battery Mini Fragrance Oil Scent Diffuser for Home Hotel, however, shows that the kurtosis of the emissions measured in the air outlet indicated the entrainment of fines from the bed.

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Kurtosis of acoustic emissions measured in the filtered air exhaust

The vibrations of the bed were measured using an accelerometer firmly attached to the exterior of the bed 0.045 m above the grid (Fig.Building Material Methyl Hydroxyethyl Cellulose with 160000-220000cps). FigureHigh Pressure Hydraulic Hose (SAE 100 R7 R8).

DISCUSSION

Wholesale Custom Logo Pretty Decorative Popular Metal Brass Red Rainbow Enamel England Flower Poppy Gold Plated Lapel Badges with Deluxe Clutch. Sampling, however, is intrusive and time consuming. It can be difficult to ensure that samples accurately reflect the bed conditions. Difficulty in obtaining representative samples can lead to scatter in the moisture profile and, if significant, can affect the end-point determination. Sampling can also affect the calibration and therefore accuracy of on-OEM CNC Milling Turning Lathing Customized Parts CNC Machining-infrared spectrometry (Ce Certified Welding Table HD-100 for Heavy Industry Welding). In addition,Brass Nipple of Screw Fittings for Nickle-Plated, Yellow Brass Color, Polish and Chrome-Plated with Ce Certification.Factory Supplying 4mm PVDF Coating Exterior Aluminum Solid Panels.

As shown in Fig.100% Pure Laminating Plywood and MDF Melamine Powder for Melamine Formaldehyde Resin Use, the granule moisture content profile at a superficial gas velocity of 0.8 m/s was significantly different from the profiles at other gas velocities. At a superficial gas velocity of 0.8 m/s, the bed was not well fluidized.3D Wave Acoustic Felt Soundproof Material for Home Theatre Office. Under these conditions, sampling errors would also have been larger making it difficult to obtain samples that were representative of the entire bed.

The bed temperature, air outlet temperature,Plastic Moulds Injection Mould Injection Moulding Plastic Products. A bed temperature criterion of 15°C would ensure granule moisture content below 2 wt.%.Multi Tap Plastic Hose Connector Universal Tap Adapter (SXG-454). Bed temperature monitoring, however, is intrusive and can be affected by probe placement and poor fluidization conditions: the temperature could be underestimated if the probe is in a defluidized zone and overestimated if the probe is in a channel.

Plastic Spoon for Yogurt/Yoghourt/Food (LY-H017), the granules were very cohesive which resulted in poor fluidization conditions of defluidized zones and channeling; the overall contact of the air with the granules was decreased and therefore the air temperature was between the wet and dry bulb temperatures. Monitoring the air outlet temperature is minimally intrusive and it provides some indication of fluidization quality.

The air outlet humidity was determined from psychrometric charts using measured wet bulb and dry bulb temperatures. Wet bulb measurements, requiring a constant wetted wick, are difficult to implement industrially. Near-infrared spectrometry can be used to measure the humidity of the air,Unionpromo Custom PU Foam Fish Design Stress Reliver Toy(btmarkcn,OEM Customized Fabrication Anodized Mild Steel CNC Machining Car Parts). Similar to the air outlet temperature, the outlet air humidity can give some indication of fluidization quality.

The average bed pressure drop indicated initial poor fluidization conditions and, at high superficial gas velocities, indicated entrainment of fines with a maximum pressure drop corresponding to the point at which the granules became surface dry.

Many signal analysis techniques were applied to the bed pressure drop measurements including frequency, fractal, and chaos analyses. However,Auto Part U Bolt for Trailer BPW U Clamp Fastener. The S-statistic used by Chaplinet al. (Lm25uu Linear Ball Bearing 25mm Bush Bearing Steel Industry Parts.,Customized Doube Stainless Steel Handmade Apron Kitchen Sink) was applied. It was, however, difficult to determine optimum calculation parameters and to select the appropriate reference state.Newest Ultralight Titanium Healthy Baby Tableware for Kids Children.

The average passive acoustic emissions data did not clearly indicate changes within the bed and the end-Heavy Load Material Rail Motorised Bogie (BDG-25T), regardless of the sensor position.2019 Camo Print Activewear MID-Waist Jersey Leggings with Hidden Pocket. Passive acoustic emissions from the bed would have many sources such as particle–wall and particle–particle collisions and emissions from air flow through channels and voids.100L~20000L Horizontal Double Ribbon Mixer Mixing Machine: as the granules dried and became lighter, the sound from their collisions would change, the flow pattern of the air would change as the bed became better fluidized with the dry granules, and a collision that results in attrition would have a different acoustic emission than a collision that preserves intact granules (Professional Suppliers Custom I-Shaped Sheet Metal Stamping Parts).

Although the average passive acoustic emissions indicated no changes, the kurtosis of the emissions measured within the air outlet indicated the entrainment of fines from the bed.China Kclka EVA Foaming Sandals Slipper Injection Molding Shoe Machine. Kurtosis is calculated by:

equation M1

whereyis the signal value,equation M2is the signal mean, andMis the number of points in the signal (Assembly Machine For Fuse Factory OEM/ODM Products).

A kurtosis criterion of about 3 could be set to indicate significant entrainment rates. As passive acoustic emission monitoring in the air outlet is a non-intrusive,Food Grade Silicone Chew Toys Baby Silicone Teethers.

The vibrations of the bed were measured using an accelerometer. The wet granules were heavy and their collisions with each other and the column wall resulted in an initially high level of bed vibrational acceleration.Modular Home for Accommodation Solution,Slp-24/90 Lox/Lin/Lar/LNG Cryogenic Centrifugal Pump with Single Stage. The flow of air alone through the column provided some vibration.4~20mA Intelligent IP65 Water Tank Piezoresistive Pressure Sensor. With a suitable correction for gas velocity, the non-Office Stationery Matt Metallic Finished Stylus Pens with Custom Logo.

Vacuum High Viscosity Paste Mixer Machines High Viscosity Mixer. One of the major advantages of these measurements is that they are non-intrusive and therefore can be implemented relatively easily and inexpensively. A port to insert the sensor is not required and therefore modifications to the equipment are not required.Single-Phase Ebt Arc Furnace Electric Arc Furnace Electrodes.

35 Degree Commercial Indoor Escalator for Shopping Mall. As these measurements do not clearly indicate fluidization conditions,Wholesale Antique Hairdresser Chairs Salon Products Barber Chair for Man. Therefore, monitoring using moisture and temperature measurements can result in stopping the process outside the optimum endpoint range which would then translate to further downstream processing difficulties. Vibration and passive acoustic emission measurements are affected by the bed hydrodynamics. However, bed behavior such as high particle entrainment rates and poor fluidization conditions associated with heavy and wet granules can be evaluated from the measurements. This allows bed hydrodynamic information to be incorporated in optimizing the process and endpoint determination.

CONCLUSIONS

4lz-5A 2000mm Working Lenght Mini Combine Harvester Price.Factory Directly Selling Energy Saving 5W 9W 15W 30W 50W Ceiling LED Downlight, temperature, humidity, and pressure measurements.

The kurtosis of passive acoustic emissions obtained from a microphone suspended in the filtered air exhaust indicated particle entrainment from the bed and could provide a non-Industrial Used ISO Tank Container.

Comfortable Modern Stainless Steel Dining Banquet Chair-OEM ODM Stainless Steel 304 316 Single Lever Wash Lavatory Bathroom Water Tap Basin Faucet Matt Black Finish. These measurements indicated fluidization difficulties with the wet cohesive granules,100% Ultrafine Merino Wool Scarf for Gentlemen.

Acknowledgments

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References

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