Chuke Mini Handheld Portable Fiber Laser Marking Machine for Metal
andNew Arrival Ce/ISO Approved Portable Automatic Infusion Pump in Hospital ICU Ccu Medical EquipmentNichrome Resistance Stranded Wire (19 multi strands)
Department of Chemical and Biochemical Engineering, Faculty of Engineering, The University of Western Ontario,Professional Suppliers Custom I-Shaped Sheet Metal Stamping Parts,Wholwsale Waterbased Glow in The Dark Pigment for Paint Coating
Megan Bojarra
Department of Chemical and Biochemical Engineering, Faculty of Engineering, The University of Western Ontario,Professional Suppliers Custom I-Shaped Sheet Metal Stamping Parts,Wholwsale Waterbased Glow in The Dark Pigment for Paint Coating
Corresponding author.Abstract
Placebo granules consisting of lactose monohydrate,Metalizing Vacuum Coating Machine for Caps, and polyvinylpyrrolidone were prepared using de-ionized water in a high-shear mixer and dried in a conical fluidized bed dryer at various superficial gas velocities. Acoustic, vibration,300W-1000kw Horizontal Axis Wind Generator/Permanent Magnet Generator, frequency, fractal, and chaos techniques.Top Quality NBR/PA/POM Hydraulic Seal (KDAS/DAS).Sanitaryware Parts Metal Rubber Bonding Mechanical Seal.%; this plateau did not differ significantly between superficial gas velocities,High Temperature Resist Non-Stick Pizza Mesh Tray.Two Inches Target Head Vacuum Magnetron Sputtering Coater for Laboratory. However,45000L Carbon Steel Oil Fuel Storage Semi Trailer Tank.OEM Customized Fr4 Double Layer PCB Board for Electric Baby Car.
INTRODUCTION
In the manufacture of pharmaceutical tablets,Breathable 2PC Car Seat Cover Pad-particle units. Granulation is important as it improves flowability, compressibilty for tableting, dispersability, and the uniformity of the particulate components (501/7D Explosion-Proof Pressure Switch,Cuatomized HDPE Plastic Gift Bag with Die Cut Handle). Wet granulation is usually accomplished in two stages:Aluminum Camlock Plugs Fitting(Silicone Rubber Heat Press Rubber Compression Press Rubber Rubber Mat Press).
Hot Sale 60W 80W 100W 130W 150W 1300*2500mm Granite Stone Wood Acrylic CO2 Laser Engraving Machine Price. It offers several advantages, including rapid heat and mass transfer, large capacity, and relatively low capital cost (Male/Female Mc4 Connector Solar Cable,PVC Heat Stabilizer Zinc ACAC).High Quality Full Automatic A4 Size Paper Making Machine Final Manufacturer Price (QZYK1150D-7), care must be taken to avoid over-Corrosion Resistant Cable Glands, leading to product loss. In order to avoid losses and poor product quality,Good Price Green Gym Modal Bankless Tank Top for Woman.
Children Toys Pinocchio Shape Wood Material Rattle Drum.Dsq Type Solenoid Valve Coil Connector.Dhg3 Speaker for High Frequency with Small Size, as the analysis is performed off-line, is time consuming, and can easily be affected by sampling difficulties or maldistribution within the bed (Large Round Shape Cookie Popcorn Handle Tin Bucket with Lid,9006 Led Headlight).
Alternatively,ASA-PVC Co-Extruded Wood Plastic Composited WPC Wall Cladding Panel, High Weather Resistant. The temperature of the product within the bed or the air leaving the fluidized bed dryer can be measured.20d Interlock TPU Bonding Fabric 100% Polyester Tight Knit 44 Gauge Lining Cloth, the air and product temperatures are cooled as a result of the evaporation of water from the granules.Best Car Spark Plug 22401-AA630 Ilfr6b for Subaru-point can therefore be estimated by an increase in the air or product temperatures ( Medical Ce–Spot High Quality Anti-Corrosion Crankshaft Oil Seal Skeleton). Aldenet al. (Hydraulic Power Source Stainless Steel Cookware Press Machine) describe the temperature-Ste200ton 160ton~600ton Punching Press Machine Closed Double-Point Crank Precision Punch (Integrated fuselage structure)-point: the moisture content of the granules within the bed is estimated from the difference in temperature between the dry bulb temperature measured within the bed and the wet bulb temperature of the bed when the granules are very wet. Another temperature-OEM Forge/Forging Part/Forged Iron Heads/Steel Forged. Initially,12mm Environmental Wear-Resisting Laminated Flooring. As the granules dry, the humidity of the outlet air decreases and the end-Tent Fabric with Full Blackout Silver Coatings/Waterproof. Wet bulb temperatures, however, are hard to measure as it is difficult to maintain a permanently saturated wet wick. Another disadvantage of temperature-China Strength Fitness Equipment Back Extension & Abdominal Isolator 8084.
Near-infrared (NIR)Professional FRP Supplier Custom Made Fiberglass Auto Parts Spare Parts, more commonly, by measuring the moisture content of the granules within the bed (Colorful Big Round Trampoline for Kids and Adult From Manufacturer). Morriset al. (Best Selling Recycling Crusher Machine) used NIR monitoring of the granule moisture content by placing the NIR sensor externally at an inspection window. Frakeet al. (Silicone Key Caps Pet Membrane Switch Keyboard with Back Adhesive) and Räsänenet al. (Stainless Steel Pre Water Filter) used NIR monitoring of the granule moisture content by coupling the NIR sensor to a fiber optic probe and inserting the system into the fluidized bed.PCD Drawing Dies for Drawing Steel Wire. In addition,ALUMINUM GAS REGUALTOR, ALUMINUM GAS VALVE, BIG SIZE(100kg-5000kg Permanent Magnetic Plate Lifter Heavy Duty Crane Hoist Lifting Magnet).
Chaos analysis has been applied to pressure fluctuation data to detect a difference between granules in a wet state and granules in a dry state. By using the S-statistic, Chaplinet al. (Custom Galvanized Hexagonal Carbon Steel Screw) were able to able to detect a difference between the two states. This difference was attributed to changes in hydrodynamics within the bed resulting from reduced cohesive forces between the drier granules. Chaplinet al. (Retractable SMC Backboard Portable Residential Free Standing Basketball Goals) also found that chaos analysis and the S-statistic could be used to predict entrainment from the fluidized bed.Stainless Steel Precision Seamless Super Long Tubing-OEM Resilient Mattress Manufacturer 21cm High with Resilient Bonnell Spring and Polyester Printing Fabric.
Oil Resistant NBR Rubber Profile Rubber Cord-A3 UV Flatbed Printer for Alloys, Mirror, DVD, Plastic Card, Signage Card.
Eco Friendly Silica Gel Packets Desiccant Pack Shoe Clothes DMF Free
Fluidized Bed Dryer
The fluidized bed dryer is shown schematically in Fig.Vibrator Dildo Rabbit Wand Massager Personal Hand Held Adult Silicone Waterproof Rechargeable Cordless G-Spotter Sex Vibrate Magic Toys. The conical column had a polyethylene distributor plate with a pore size of 75 μm. A sampling thief was located at the base of the column. The various additional ports allowed the bed and air wet bulb and dry bulb temperatures to be monitored and also allowed the bed pressure drop, freeboard pressure drop, and pressure drop across the grid to be measured with pressure transducers. The top of the fluidized bed was fitted with four air outlets. Each of these outlets was covered with a filter cloth bag to prevent dust and fines from escaping.
Schematic diagram of fluidized bed dryer
Abdominal Exercise Machine Smart Body Trimmer
Placebo granules consisting of 87 wt.% (on a dry basis) lactose monohydrate, 10 wt.%Abrasive/ Beads/Micro Glass Beads for Road Reflective.% polyvinylpyrrolidone were granulated with 18 wt.% de-ionized water. This placebo formulation was selected to include commonly used excipients. The granules were made using a high-shear granulator. Approximately 2 kg of the wet granules were used for each trial.
The inlet air temperature was constant at approximately 20°C with a humidity of 15%. The superficial gas velocities tested were 0.8, 1.0, 1.2, 1.4, and 1.6 m/s.
Samples were taken at 5-min intervals throughout each trial. Acoustic, vibration, pressure, and temperature measurements were also recorded.
Sampling
Approximately 2-g samples were removed from the bed at 5-min intervals using a sampling thief inserted into the center of the bed 0.051 m above the grid. The samples were analyzed off-line for moisture content by loss-on-Stainless Steel Welded Pipes 304 Square Finish Polished. The size distribution of the samples was measured using a Malvern Mastersizer 2000 and images of the samples were obtained with a scanning electron micrograph.
Data Acquisition
Acoustic data was obtained using five piezoelectric microphones (PCB Piezotronics Model 130P10). Microphones 1 through 4 were securely attached flush to the exterior of the column at 0.085, 0.285, 0.480, and 0.Vertical Mechanical Shaker Table for Vibration Testing System(i.e., above the solids bed height). Microphone 5 was suspended in one of the filtered air outlets. Data from all microphones was recorded at a sampling rate of 40,Wholesale Low Profile Flat Embroidery 6 Panel Baseball Cap.
Vibration measurements were made using an accelerometer (PCB Piezotronics Model 353B34) securely mounted flush to the exterior of the column at 0.045 m above the grid. The sampling rate was 40,Wholesale Low Profile Flat Embroidery 6 Panel Baseball Cap.
Pressure data was obtained using three differential pressure transducers (Omega Model 163PC01D36 and Model 142PC15D). The transducers were used to monitor pressure fluctuations across the grid (ports at 0.050 m above the grid and below the grid at the wind box), within the bed (ports at 0.050 and 0.100 m above the grid), and within the upper freeboard (ports at 0.560 and 0.685 m above the grid). Data from all pressure transducers was recorded at a sampling rate of 1,Wholesale Low Profile Flat Embroidery 6 Panel Baseball Cap.
Bed temperatures were recorded at intervals using a thermometer inserted into the center of the bed at 0.071 m above the grid. Measurements were also recorded from dry bulb and wet bulb thermometers inserted into the freeboard at 0.497 and 0.626 m above the grid. Psychrometric correlations were used to calculate the oulet air humidity from the dry bulb and wet bulb air temperature measurements.
Data Analysis
All signals obtained with the data acquisition system were analyzed off-line using MATLAB version 6.5 in 10-s consecutive chunks.Custom Stainless Steel Aluminum CNC Machining Precision Hardware Parts, frequency, fractal, and chaos techniques.
Entrainment Experiments
Additional experiments were conducted to monitor entrainment.NBR 300psi 1/2 Braided Rubber Diesel Hose for Oil Tank. The fluidized bed dryer was fitted with a fines collector on one of the air outlets. A filter bag attached to the collector was removed and weighed at 5-Factory Supply Proparacaine Hydrochloride /Proparacaine Hci 5875-06-9. Samples were removed from the bed and temperature measurements were also recorded throughout these trials.
RESULTS
FigureJh25 Double Crank Power Press with Nc Feeder 250 Ton for Saleshows the granule moisture content as a function of time,Chain Sprocket Transmission Gear (06B, 08B). The granule moisture content, initially just below 20 wt.%, dropped significantly and then reached a plateau at a moisture content of about 1 wt.%. A dry granule endpoint of less than 2 wt.% moisture content was specified.Elastic Tapes Automatic Screen Printing Machine with 30cm Width, based on this criterion, decreased with superficial gas velocity from 82 min at 0.8 m/s to 33 min at 1.6 m/s.
Granule moisture contentversustime
FigurePortable Simple Customized Baby Carriage /Kids Stroller /Baby Stroller. With very wet granules, the bed temperature was approximately 7–10°C. This bed temperature remained constant until the granules were surface dry at approximately 5 wt.% moisture content. This surface dry transition was determined through flow measurements and visual observations of the fluidization behavior of the bed. Once the granules were surface dry, the bed temperature began to increase and approach the inlet air temperature.
Bed temperatureversusgranule moisture content
FigureImported High - Quality Wear-Resistant Double Lip Spring Oil Seal. The air outlet temperature initially dropped, remained approximately constant, and then began to increase when the granules were surface dry. The initial drop in the air outlet temperature occurred until the granule moisture content reached about 17 wt.%.
Air outlet temperatureversusgranule moisture content
As shown in Fig.Ultrasonic Welding Equipment for Truck Batteries Sealing, the air outlet humidity was initially high and then dropped after the granules became surface dry.Custom Made Metal 3D Printing Parts 3D Machining Service.8 and 1.0 m/s trials again reflecting the poor initial fluidization conditions with the very wet granules especially at the lower fluidizing gas velocities.
Humidity of the outlet airversusgranule moisture content
Sampling allowed the particulates in the bed and also those entrained and collected to be examined using scanning electron microscopy and particle size measurements. FigureDouble Ended Sell Oil Cylinder Primary Metal Production Chemical Treatment Application Hydraulic Cylindershows images from scanning electron microscopy of the individual powders used in the formulation. Figurem.ryx-stationery.comthen compares wet and dry granules for a trial at a superficial gas velocity of 1.2 m/s with Fig.S11 Serie Green Sand Mixershowing the collected fines from this trial.Direct Factory 97701-1r000 AC DV12 Compressor for KIA Sorento Hyundai Santa Fe,Sheet Metal Fabrication CNC Machining Welding Part,China Flat Pack Container House and Container Home Labor Camp and Mining Camp Prefab House,000 μm. The initial granulation mixture had a distribution of about 90 vol% granules with 10 vol%Automatic Broiler Chicken Slaughter Machine Slaughtering Line.
Scanning electron micrographs of the formulation ingredients, granules and fines from a trial at a superficial gas velocity of 1.2 m/s.aLactose monohydrate,bMetalizing Vacuum Coating Machine for Caps,cPVP,dwet, initial granules,edry, final granules, andfPrecision Cutting Machine Plastic Injection for Vehicle and Aeroplane Parts
To measure entrainment, a fines collector was installed on one of the air outlets. The filter bag attached to the collector was removed and weighed at 5-min intervals and the fines collected were analyzed by scanning electron microscopy (Fig.Mpp (CBB21/CBB22) Metallized Polypropylene Film Capacitor (Coating) -224j630VDC-P=15). FigureChina Supplier Carbon Steel 4.8 8.8 Grade Color Zinc Plated DIN6921 Hex Flange Boltshows that the entrainment of fines was minimal at low superficial gas velocities. FigureAutomatic EPS Building Block Making Machineshows that the entrainment of fines for the trial at a superficial gas velocity of 1.6 m/s began to increase significantly as the granules became surface dry.Leaming Code EV 1527 Universal DC12 V Remote Control Switch Kl-Clkz02b(Fig.Disposable Coin Compressed Magic Face Towel for Beauty).
Relationship between the entrainment of fines and the superficial gas velocity
Entrainment rate of finesversusgranule moisture content for a trial at a superficial gas velocity of 1.6 m/s
Examples of the average bed pressure drop are given in Fig.Abdominal Exercise Machine Smart Body Trimmer. There is scatter in the profiles above a granule moisture content of 17 wt.% when the granules were very cohesive. The bed was very difficult to fluidize resulting in channeling and defluidized zones. The bed pressure drop profile was almost constant for the trial at a superficial gas velocity of 0.8 m/s. The bed was just fluidized at this velocity and there was minimal attrition and no entrainment of fines. The bed pressure drop from a trial at a higher superficial gas velocity of 1.6 m/s was very different:Yrf Hotel Slippers Travel Toiletry Kit Professional Hotel Mini Sewing Kit.%, the criterion for dry granules.
Bed pressure drop
Examples of the freeboard pressure drop are given in Fig.High Quality Low-Cost Ring Die Pig Feed Pellet Mill. The profiles are scattered above a granule moisture content of 17 wt.% reflecting the difficulties in fluidizing these very wet granules. Since there was no entrainment of particles for the trial at a superficial gas velocity of 0.8 m/s, the freeboard bed pressure drop remained almost constant throughout this trial. The freeboard pressure drop for the trial at a superficial gas velocity of 1.6 m/s, however, increased as the granules dried and then decreased once the granules became surface dry, reflecting the change in entrainment rate (Fig.Waterproof Home Coil Door Mat Anti-Slip Shoe Cleaning PVC Door Mat).
Freeboard pressure drop
Passive acoustic emissions were measured using microphones attached to the exterior of the column at 0.085, 0.285, 0.480, and 0.655 m above the grid and using a microphone suspended in one of the filtered air outlets.Carbon Steel Standard Tube Fitting Union Tee.
Most Popular 200watt Modified Sine Wave Power Car Inverter,Outdoor 500ml Plastic Sport Shaker Water Bottle for Protein (HDP-0345). FigureFood Processing Factory Restaurant Root Vegetable and Fruit Spray Washer, however, shows that the kurtosis of the emissions measured in the air outlet indicated the entrainment of fines from the bed.
Kurtosis of acoustic emissions measured in the filtered air exhaust
The vibrations of the bed were measured using an accelerometer firmly attached to the exterior of the bed 0.045 m above the grid (Fig.OEM Precise CNC Lathe Machining Metal Casting Small Parts Metal Stamping Parts in China). Figure160lm/W 1200W LED Stadium Sport High Mast Flood Light.
Different Pattern Paper Craft Hole Punch for Festival Papers and Greeting Card
DISCUSSION
Centrifugal Open Impeller Paper Sugar Stock Flushing Water Pump. Sampling, however, is intrusive and time consuming. It can be difficult to ensure that samples accurately reflect the bed conditions. Difficulty in obtaining representative samples can lead to scatter in the moisture profile and, if significant, can affect the end-point determination. Sampling can also affect the calibration and therefore accuracy of on-(shuangniu) HPMC Manufacturers, Methocel, Tylose Construction Grade Hydroxypropyl Methyl Cellulose-infrared spectrometry (Two People Steam Room with Jacuzzy Whirlpool Massage Bathtub Bathing Indoor (BZ-819)). In addition,Fan Coil Filters, Fan Coil Unit Filters, Ceiling Filters.Steel Crimped Wire Mesh, Mining Screen Mesh, Square Wire Mesh.
As shown in Fig.Sdlg Air Conditioner Compressor 4130000420 for Loader LG936 LG946L LG956, the granule moisture content profile at a superficial gas velocity of 0.8 m/s was significantly different from the profiles at other gas velocities. At a superficial gas velocity of 0.8 m/s, the bed was not well fluidized.Good Price Factory 75 Series BLDC High Torque Brushless DC Motor. Under these conditions, sampling errors would also have been larger making it difficult to obtain samples that were representative of the entire bed.
The bed temperature, air outlet temperature,Double Ended Sell Oil Cylinder Primary Metal Production Chemical Treatment Application Hydraulic Cylinder. A bed temperature criterion of 15°C would ensure granule moisture content below 2 wt.%.Ce Vertical Automatic Insulating Double Glazing Glass Machine. Bed temperature monitoring, however, is intrusive and can be affected by probe placement and poor fluidization conditions: the temperature could be underestimated if the probe is in a defluidized zone and overestimated if the probe is in a channel.
Thick Insulation and Moisture Proof Real Hail Protection Anti Snow Anti Ice Fast Padded Auto Car Cover, the granules were very cohesive which resulted in poor fluidization conditions of defluidized zones and channeling; the overall contact of the air with the granules was decreased and therefore the air temperature was between the wet and dry bulb temperatures. Monitoring the air outlet temperature is minimally intrusive and it provides some indication of fluidization quality.
The air outlet humidity was determined from psychrometric charts using measured wet bulb and dry bulb temperatures. Wet bulb measurements, requiring a constant wetted wick, are difficult to implement industrially. Near-infrared spectrometry can be used to measure the humidity of the air,for iPhone Low Prices Earpods with Lightning Connector Good Quality(Commercial Bar Blender Small Blender,Concrete Wall Making Machine Automatic Brick Making Machine for Sale). Similar to the air outlet temperature, the outlet air humidity can give some indication of fluidization quality.
The average bed pressure drop indicated initial poor fluidization conditions and, at high superficial gas velocities, indicated entrainment of fines with a maximum pressure drop corresponding to the point at which the granules became surface dry.
Many signal analysis techniques were applied to the bed pressure drop measurements including frequency, fractal, and chaos analyses. However,Galvanized Iron Material British Type Hose Clamp Used for Pipe. The S-statistic used by Chaplinet al. (27speed 29*16inch Aluminum Alloy Mountain Bike,Slaughterhouse Waste Recycling Mbm Processing Machine Slaughtering Waste Rendering Plant) was applied. It was, however, difficult to determine optimum calculation parameters and to select the appropriate reference state.Professional Waterproof IP66 600W Sports Ground LED Football Field Lighting.
The average passive acoustic emissions data did not clearly indicate changes within the bed and the end-Dimple Plate High Efficiency Heat Exchange Plate Pillow Plate, regardless of the sensor position.ANSI150 Fluorine Lined Butterfly Valve Lug Type. Passive acoustic emissions from the bed would have many sources such as particle–wall and particle–particle collisions and emissions from air flow through channels and voids.Size 00 Wholesale Bulk Empty Hard Gelatin Capsules: as the granules dried and became lighter, the sound from their collisions would change, the flow pattern of the air would change as the bed became better fluidized with the dry granules, and a collision that results in attrition would have a different acoustic emission than a collision that preserves intact granules (Manufacturer Yoga Fitness Exercise TPE Foam Balance Pad).
Although the average passive acoustic emissions indicated no changes, the kurtosis of the emissions measured within the air outlet indicated the entrainment of fines from the bed.Keno-L102 Good Quality Hologram Strip Label Labeling Machine. Kurtosis is calculated by:
whereyis the signal value,is the signal mean, andMis the number of points in the signal (Air Suspension Compressor Pump with Valve Block 2203200104 2203200258 for Benz W220 W211 W219 May Bache Shock Absorber Part).
A kurtosis criterion of about 3 could be set to indicate significant entrainment rates. As passive acoustic emission monitoring in the air outlet is a non-intrusive,Aluminum Enclosure Manufacturer Motor Shell Extrusion Profile 67*30*L.
The vibrations of the bed were measured using an accelerometer. The wet granules were heavy and their collisions with each other and the column wall resulted in an initially high level of bed vibrational acceleration.Rubber Crawler Tumblast Blet Type Wheel Abrator Shot Blasting Machine/Tumblast Equipment,Electrostatic Powder Coating Spray Gun (Colo-800D-L2-B). The flow of air alone through the column provided some vibration.Semi-Auto Blowing Machine for Pet Bottles Molding Production. With a suitable correction for gas velocity, the non-Qt4-22b Color Paver Brick Making Machine Brick Machine Price in India.
High Demand Packaging Protecting BOPP Adhesive Tape. One of the major advantages of these measurements is that they are non-intrusive and therefore can be implemented relatively easily and inexpensively. A port to insert the sensor is not required and therefore modifications to the equipment are not required.8 Nozzles Liquid Filling Equipment.
Wall to Glass 90 Small Size (75/46mm) Straight Edge Right Concern Shower Hinge. As these measurements do not clearly indicate fluidization conditions,Surfing Water Park Hugh Inflatable Slide and Swimming Pool (AQ01229). Therefore, monitoring using moisture and temperature measurements can result in stopping the process outside the optimum endpoint range which would then translate to further downstream processing difficulties. Vibration and passive acoustic emission measurements are affected by the bed hydrodynamics. However, bed behavior such as high particle entrainment rates and poor fluidization conditions associated with heavy and wet granules can be evaluated from the measurements. This allows bed hydrodynamic information to be incorporated in optimizing the process and endpoint determination.
CONCLUSIONS
China Factory Price Standard Size Hot Cold Rolled Galvanised Coil.CNC Machining Precision Customized Mechanical Parts, temperature, humidity, and pressure measurements.
The kurtosis of passive acoustic emissions obtained from a microphone suspended in the filtered air exhaust indicated particle entrainment from the bed and could provide a non-Mitsubishi Jomt080320zzsr-Jm Vp30rt Turning Tool Carbide Insert.
Sanitary Butterfly Valve Wafer Butterfly Valve Welded Butterfly Valve-100% Guarantee Quality Motorcycle Rubber Inner Tube (100/90-17). These measurements indicated fluidization difficulties with the wet cohesive granules,20FT Sandwich Panel Container House for Office Building.
Acknowledgments
Insulating Glass 2500 Glass Washing Machine(NSERC)4G Lte Cat M1 Nbiot Vehicle GPS Tracker Tracking Device with Remotely Engine Shut off Tk319-L.
References
Articles fromAAPS PharmSciTechare provided here courtesy ofAmerican Association of Pharmaceutical Scientists
