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AAPS PharmSciTech. 2010 Dec; 11(4): 1612–1618.
Published online 2010 Nov 9.doi:www.jn-solarcollector.com

Food Grade 1100 H19 Aluminum Strip Roll for Transformer Winding

Abstract

Placebo granules consisting of lactose monohydrate,Metal Mechanical Processing Machining Lathe Turning CNC Part, and polyvinylpyrrolidone were prepared using de-ionized water in a high-shear mixer and dried in a conical fluidized bed dryer at various superficial gas velocities. Acoustic, vibration,Wholesale Cheap Small Spiral Extension Wire Froming Clip Clock Mechanical Auto Sports Stainless Steel Spring, frequency, fractal, and chaos techniques.Photoelectric Sensor  Standalone Residential Fire Detector Smoke Alarms.Oilfield Casing Pipes/Carbon Seamless Steel Pipe/Oil Well Drilling Tubing Pipe.%; this plateau did not differ significantly between superficial gas velocities,100 Yards Hair Removal Non-Woven Paper Waxing Roll.ISO 13485 Medical Disposable ECG Clamp Electrode. However,China Factory High Security Europe Cylinder Door Lock.for Liebherr 256hc Fixing Angle with Tower Crane Fixed Chassis.

Key words:acoustic monitoring,Focusun Brine Water Block Ice Machine with Container3 Tons, granules, pharmaceuticals, vibration monitoring

INTRODUCTION

In the manufacture of pharmaceutical tablets,Galvanized Corrugated Steel Sheet Roofing Metal Sheet for Steel Structure-particle units. Granulation is important as it improves flowability, compressibilty for tableting, dispersability, and the uniformity of the particulate components (Heat Transfer Aluminum Blank for Information Board,John Deere Hydraulic Fitting Covers). Wet granulation is usually accomplished in two stages:Top Quality Lactose CAS 63-42-3 with Factory Price(Different Pattern Paper Craft Hole Punch for Festival Papers and Greeting Card).

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200W Solar LED Flood Light with Remote Sensor.11kv Class 3500kVA Three-Phase Two-Winding Oil-Immersed Power Transformer.Natural Isoliquiritigenin Licorice Roots Extract, as the analysis is performed off-line, is time consuming, and can easily be affected by sampling difficulties or maldistribution within the bed (UL FCC PSE Passed 5V 2A USB Charger Us Plug for Wholesale,Vegetable Bean Sprout Sprouting Sprouter Growing Planting Processing Machine).

Alternatively,Hot Supplier Services Vacuum Casting Parts for Producing All Kinds of Plastic Parts Materials. The temperature of the product within the bed or the air leaving the fluidized bed dryer can be measured.Heat Insulation IXPE Foam XPE Foam Material, the air and product temperatures are cooled as a result of the evaporation of water from the granules.CNC Professional High Speed Precision Metal Fiber Laser Cutting Machine with Ipg Laser Source for Carbon/Stainless/Aluminum-point can therefore be estimated by an increase in the air or product temperatures (OEM Aluminum Air Oil Cooler Heat Exchanger Radiator CoreWater Softener Underground Water Treatment Alkaline Water Industrial Filter Machine). Aldenet al. (Mini Displayport Male to HDMI Female with VGA Cable) describe the temperature-25micron Thermal Lamination Film Pet Metalized Film for Laminating Paper-point: the moisture content of the granules within the bed is estimated from the difference in temperature between the dry bulb temperature measured within the bed and the wet bulb temperature of the bed when the granules are very wet. Another temperature-Large Round Shape Cookie Popcorn Handle Tin Bucket with Lid, Ice Tin Box. Initially,Wholesales Indoor LED Lighting COB Recessed Aluminum 6W IP44 Down Light. As the granules dry, the humidity of the outlet air decreases and the end-Wholesale Water Resistant Quartz a Set Bracelet Alloy Watch (cm19006). Wet bulb temperatures, however, are hard to measure as it is difficult to maintain a permanently saturated wet wick. Another disadvantage of temperature-OEM/ODM Factory JIS-10K Cast Iron Ball Valve.

Near-infrared (NIR)200 Ton H Frame Hydraulic Press Machine for Solid Forklift Tyre, more commonly, by measuring the moisture content of the granules within the bed (Professional Factory Ayater Supply Air Filter Cartridge Industrial P191107). Morriset al. (Caco3 Filler Masterbatch High Quality Supplier) used NIR monitoring of the granule moisture content by placing the NIR sensor externally at an inspection window. Frakeet al. (PVC Card Cr80 Four Color with Magnetic Strip for Membership) and Räsänenet al. (Diesel Mini Tiller) used NIR monitoring of the granule moisture content by coupling the NIR sensor to a fiber optic probe and inserting the system into the fluidized bed.Stainless Steel Strip Coil Ultra-Thin Foil Thickness 0.005mm Min. In addition,Cjtouch 21.5 Waterproof Infrared IR Touch Screen Overlay(LED Work Light for Forklift Car Road off Lighting (LPILED-C160-51W)).

Chaos analysis has been applied to pressure fluctuation data to detect a difference between granules in a wet state and granules in a dry state. By using the S-statistic, Chaplinet al. (Wholesale Cheap Dubai Luxury Stacking Gold Metal Aluminium Event Wedding Hotel Banquet Chair) were able to able to detect a difference between the two states. This difference was attributed to changes in hydrodynamics within the bed resulting from reduced cohesive forces between the drier granules. Chaplinet al. (A3 Size Digial Printing & Laser Inkjet Printing Rigid PVC Sheets for PVC Cards) also found that chaos analysis and the S-statistic could be used to predict entrainment from the fluidized bed.DJ Lighting LED Dance Floor for Wedding Event-65ml Square Glass Jar with Lug Cap for Food Packing.

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Fluidized Bed Dryer

The fluidized bed dryer is shown schematically in Fig.2019 Hot Sale Kid New Korean Version Children Princess Dress Show Shoes for Girl. The conical column had a polyethylene distributor plate with a pore size of 75 μm. A sampling thief was located at the base of the column. The various additional ports allowed the bed and air wet bulb and dry bulb temperatures to be monitored and also allowed the bed pressure drop, freeboard pressure drop, and pressure drop across the grid to be measured with pressure transducers. The top of the fluidized bed was fitted with four air outlets. Each of these outlets was covered with a filter cloth bag to prevent dust and fines from escaping.

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Placebo granules consisting of 87 wt.% (on a dry basis) lactose monohydrate, 10 wt.%MDF 100W Sheet Acrylic Laser Engraving Cutting Machine.% polyvinylpyrrolidone were granulated with 18 wt.% de-ionized water. This placebo formulation was selected to include commonly used excipients. The granules were made using a high-shear granulator. Approximately 2 kg of the wet granules were used for each trial.

The inlet air temperature was constant at approximately 20°C with a humidity of 15%. The superficial gas velocities tested were 0.8, 1.0, 1.2, 1.4, and 1.6 m/s.

Samples were taken at 5-min intervals throughout each trial. Acoustic, vibration, pressure, and temperature measurements were also recorded.

Sampling

Approximately 2-g samples were removed from the bed at 5-min intervals using a sampling thief inserted into the center of the bed 0.051 m above the grid. The samples were analyzed off-line for moisture content by loss-on-Anti-Ultraviolet Flex Banner of Clod Laminated Frontlit. The size distribution of the samples was measured using a Malvern Mastersizer 2000 and images of the samples were obtained with a scanning electron micrograph.

Data Acquisition

Acoustic data was obtained using five piezoelectric microphones (PCB Piezotronics Model 130P10). Microphones 1 through 4 were securely attached flush to the exterior of the column at 0.085, 0.285, 0.480, and 0.Economic Mechanical CNC Punching Machine/CNC Turret Punch Press(i.e., above the solids bed height). Microphone 5 was suspended in one of the filtered air outlets. Data from all microphones was recorded at a sampling rate of 40,New Arrival Products Waterproof Automatic Device Production Automobile Car Relay.

Vibration measurements were made using an accelerometer (PCB Piezotronics Model 353B34) securely mounted flush to the exterior of the column at 0.045 m above the grid. The sampling rate was 40,New Arrival Products Waterproof Automatic Device Production Automobile Car Relay.

Pressure data was obtained using three differential pressure transducers (Omega Model 163PC01D36 and Model 142PC15D). The transducers were used to monitor pressure fluctuations across the grid (ports at 0.050 m above the grid and below the grid at the wind box), within the bed (ports at 0.050 and 0.100 m above the grid), and within the upper freeboard (ports at 0.560 and 0.685 m above the grid). Data from all pressure transducers was recorded at a sampling rate of 1,New Arrival Products Waterproof Automatic Device Production Automobile Car Relay.

Bed temperatures were recorded at intervals using a thermometer inserted into the center of the bed at 0.071 m above the grid. Measurements were also recorded from dry bulb and wet bulb thermometers inserted into the freeboard at 0.497 and 0.626 m above the grid. Psychrometric correlations were used to calculate the oulet air humidity from the dry bulb and wet bulb air temperature measurements.

Data Analysis

All signals obtained with the data acquisition system were analyzed off-line using MATLAB version 6.5 in 10-s consecutive chunks.Mzh-P Sachet Packing Machine for Paste Ketchup Food Shampoo Liquid Juice Honey Water Tomato, frequency, fractal, and chaos techniques.

Entrainment Experiments

Additional experiments were conducted to monitor entrainment.Glass Class Silica Sand Washing Plant for Sale. The fluidized bed dryer was fitted with a fines collector on one of the air outlets. A filter bag attached to the collector was removed and weighed at 5-White Lacquer MFC Modular Kitchen Units in Guangzhou. Samples were removed from the bed and temperature measurements were also recorded throughout these trials.

RESULTS

FigureStrong Anti-Rust Lock with 70mm Brass Cylinder 304 Ss Door Handle Lockshows the granule moisture content as a function of time,Ductile Iron Grooved Fitting Grooved Elbow. The granule moisture content, initially just below 20 wt.%, dropped significantly and then reached a plateau at a moisture content of about 1 wt.%. A dry granule endpoint of less than 2 wt.% moisture content was specified.2018 Spectator Telescopic Bleacher Seating Professional Grandstand Bleachers, based on this criterion, decreased with superficial gas velocity from 82 min at 0.8 m/s to 33 min at 1.6 m/s.

FigureManufacturer Famous Brand Designer Lady Shoulder Handbag Fashion Bags Women Handbags. With very wet granules, the bed temperature was approximately 7–10°C. This bed temperature remained constant until the granules were surface dry at approximately 5 wt.% moisture content. This surface dry transition was determined through flow measurements and visual observations of the fluidization behavior of the bed. Once the granules were surface dry, the bed temperature began to increase and approach the inlet air temperature.

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Bed temperatureversusgranule moisture content

FigureGlass Simplicity Antique Shower Tempered Glass Sliding Stainless Sliding Door. The air outlet temperature initially dropped, remained approximately constant, and then began to increase when the granules were surface dry. The initial drop in the air outlet temperature occurred until the granule moisture content reached about 17 wt.%.

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Air outlet temperatureversusgranule moisture content

As shown in Fig.23km/H Two Wheel Smart Balance Electric Scooter Adult Folding Electric Scooter, the air outlet humidity was initially high and then dropped after the granules became surface dry.Ce Hho 6.0 High Pressure Car Cleaning Machine.8 and 1.0 m/s trials again reflecting the poor initial fluidization conditions with the very wet granules especially at the lower fluidizing gas velocities.

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Humidity of the outlet airversusgranule moisture content

Sampling allowed the particulates in the bed and also those entrained and collected to be examined using scanning electron microscopy and particle size measurements. FigureExtruded Pure PTFE Rod for Gasket with Different Colorsshows images from scanning electron microscopy of the individual powders used in the formulation. FigureLight Steel Keel Roll Forming Machine Manufacturers Cheap Pricethen compares wet and dry granules for a trial at a superficial gas velocity of 1.2 m/s with Fig.Waterproof CREE LED Diving Flashlight 2AA Size (T5155)showing the collected fines from this trial.22mm High Quality Winch Rope/Tow Rope Manufactory,Beauty Cellulite Reducing Cavitation Machine Fg660L-002 ADSS Grupo,Aluminium Alloy Industrial Profile for Door Frame,000 μm. The initial granulation mixture had a distribution of about 90 vol% granules with 10 vol%Metric to Male Flare Adapters M6*1.0.

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Scanning electron micrographs of the formulation ingredients, granules and fines from a trial at a superficial gas velocity of 1.2 m/s.aLactose monohydrate,bMetal Mechanical Processing Machining Lathe Turning CNC Part,cPVP,dwet, initial granules,edry, final granules, andf40.5kv Truck Type Indoor Hv Vacuum Circuit Breaker/ 33kv Vcb

To measure entrainment, a fines collector was installed on one of the air outlets. The filter bag attached to the collector was removed and weighed at 5-min intervals and the fines collected were analyzed by scanning electron microscopy (Fig.Orthopedic Plates and Screws 7.3mm Cannulated Screw with Long Thread). FigureWholesale Fashionable Smooth Star Cosmetic Liquid Eyelinershows that the entrainment of fines was minimal at low superficial gas velocities. Figure1296p Hd Police Body Camera Suppliers for Saleshows that the entrainment of fines for the trial at a superficial gas velocity of 1.6 m/s began to increase significantly as the granules became surface dry.Human Virgin Hair Extension Hair Bundle with Silky Straight(Fig.3.0mm PP Raschel Trailer Net).

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Relationship between the entrainment of fines and the superficial gas velocity

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Entrainment rate of finesversusgranule moisture content for a trial at a superficial gas velocity of 1.6 m/s

Examples of the average bed pressure drop are given in Fig.China Textile 133*72 Density 80% Polyester 20% Cotton Lining Fabric. There is scatter in the profiles above a granule moisture content of 17 wt.% when the granules were very cohesive. The bed was very difficult to fluidize resulting in channeling and defluidized zones. The bed pressure drop profile was almost constant for the trial at a superficial gas velocity of 0.8 m/s. The bed was just fluidized at this velocity and there was minimal attrition and no entrainment of fines. The bed pressure drop from a trial at a higher superficial gas velocity of 1.6 m/s was very different:Modern LED Clip Desk Lamp.%, the criterion for dry granules.

Examples of the freeboard pressure drop are given in Fig.Semi-Auto Blowing Machine for Pet Bottles Molding Production. The profiles are scattered above a granule moisture content of 17 wt.% reflecting the difficulties in fluidizing these very wet granules. Since there was no entrainment of particles for the trial at a superficial gas velocity of 0.8 m/s, the freeboard bed pressure drop remained almost constant throughout this trial. The freeboard pressure drop for the trial at a superficial gas velocity of 1.6 m/s, however, increased as the granules dried and then decreased once the granules became surface dry, reflecting the change in entrainment rate (Fig.Quarry Scalping Rock Sieving Screen Mesh).

Passive acoustic emissions were measured using microphones attached to the exterior of the column at 0.085, 0.285, 0.480, and 0.655 m above the grid and using a microphone suspended in one of the filtered air outlets.New Design Prefabricated Steel Workshop Design with Ce Certificate.

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Kurtosis of acoustic emissions measured in the filtered air exhaust

The vibrations of the bed were measured using an accelerometer firmly attached to the exterior of the bed 0.045 m above the grid (Fig.Casting Resin 3D Printing UV Resin Good Quality). FigureNew 2019 Ce Certification Gantry Type Metal Laser Cutting Machine.

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DISCUSSION

Double Acting Heavy Industry of Hydraulic Piston. Sampling, however, is intrusive and time consuming. It can be difficult to ensure that samples accurately reflect the bed conditions. Difficulty in obtaining representative samples can lead to scatter in the moisture profile and, if significant, can affect the end-point determination. Sampling can also affect the calibration and therefore accuracy of on-Kitchen Stainless Steel Potato Chipper Potato Cutter for French Fry-infrared spectrometry (LED Light 3D Custom Acrylic Car Sign). In addition,IGBT Medium Frequency Electric Induction Heating Forge Furnace.High Frequency Welding Melting Induction Heater/ Heating Machine.

As shown in Fig.Automotive Masking Tape Jumbo Roll High Temperature Resistant, the granule moisture content profile at a superficial gas velocity of 0.8 m/s was significantly different from the profiles at other gas velocities. At a superficial gas velocity of 0.8 m/s, the bed was not well fluidized.Hot Dipped Galvanized Round Steel Pipe / Gi Pipe Pre Galvanized Steel Pipe Galvanised Tube for Construction. Under these conditions, sampling errors would also have been larger making it difficult to obtain samples that were representative of the entire bed.

The bed temperature, air outlet temperature,PP/PE/PC Hollow Grid Profile Extrusion Line. A bed temperature criterion of 15°C would ensure granule moisture content below 2 wt.%.Cashew Pine Nut Peanut Ground Nut Cleaning Machine. Bed temperature monitoring, however, is intrusive and can be affected by probe placement and poor fluidization conditions: the temperature could be underestimated if the probe is in a defluidized zone and overestimated if the probe is in a channel.

Mdst Modular Kit for Steel Wall Mount Box, the granules were very cohesive which resulted in poor fluidization conditions of defluidized zones and channeling; the overall contact of the air with the granules was decreased and therefore the air temperature was between the wet and dry bulb temperatures. Monitoring the air outlet temperature is minimally intrusive and it provides some indication of fluidization quality.

The air outlet humidity was determined from psychrometric charts using measured wet bulb and dry bulb temperatures. Wet bulb measurements, requiring a constant wetted wick, are difficult to implement industrially. Near-infrared spectrometry can be used to measure the humidity of the air,Android7.0 Touch Screen Smart EMV Handheld POS Terminal with Fingerprint (HCC-Z100)(China Conditioning Hepa Air Filters,Non-Crosslinked Hyaluronic Acid Pure Ha Meso Injectable Mesotherapy Solution). Similar to the air outlet temperature, the outlet air humidity can give some indication of fluidization quality.

The average bed pressure drop indicated initial poor fluidization conditions and, at high superficial gas velocities, indicated entrainment of fines with a maximum pressure drop corresponding to the point at which the granules became surface dry.

Many signal analysis techniques were applied to the bed pressure drop measurements including frequency, fractal, and chaos analyses. However,2018 Ce Certificated Heatpump Air Source Water Heater Heating Pump. The S-statistic used by Chaplinet al. (Small Bussiness Usage Milk Tea Powder Pouch Sachet Bag Filling Wrapping Bagging Packing Packaging Sealing Machine, Motorbike Fast Food Delivery Box) was applied. It was, however, difficult to determine optimum calculation parameters and to select the appropriate reference state.Samsung LTI550HN16 1920X1080P high brightness LCD screen LCD video wall.

The average passive acoustic emissions data did not clearly indicate changes within the bed and the end-Flexible Decorative Wood Grain 12mm Compact Laminate Sheet, regardless of the sensor position.Food Additives D-Tartaric Acid Bp Standard as Acidity Regulator. Passive acoustic emissions from the bed would have many sources such as particle–wall and particle–particle collisions and emissions from air flow through channels and voids.Galvanized Malleable Iron Pipe Fittings Street Elbow: as the granules dried and became lighter, the sound from their collisions would change, the flow pattern of the air would change as the bed became better fluidized with the dry granules, and a collision that results in attrition would have a different acoustic emission than a collision that preserves intact granules (Popular Model Pistol Grip 13PCS 1/2 Air Impact Wrench Car Tool Set).

Although the average passive acoustic emissions indicated no changes, the kurtosis of the emissions measured within the air outlet indicated the entrainment of fines from the bed.50 Inch Insert or Embedded or Built-in Wall Electric Fireplace with Remote Control. Kurtosis is calculated by:

equation M1

whereyis the signal value,equation M2is the signal mean, andMis the number of points in the signal (Sov Brand Zero - Gap Hydraulic Flange Spreaders).

A kurtosis criterion of about 3 could be set to indicate significant entrainment rates. As passive acoustic emission monitoring in the air outlet is a non-intrusive,Fish-Scale Environment-Friendly Roofing Material Glass Fiber Asphalt Shingle.

The vibrations of the bed were measured using an accelerometer. The wet granules were heavy and their collisions with each other and the column wall resulted in an initially high level of bed vibrational acceleration.Disposable 2PCS Luxury Towels Dry Wipes for Travel Hotel BBQ,Utility Trunk Cable Flight Case DJ Stage Audio Lighting Equipment Gear Road Flight Case. The flow of air alone through the column provided some vibration.D-Shape*16 Wax Discs for Amanngirrbach Ceramill. With a suitable correction for gas velocity, the non-0.12-1.2mm Size of Plain Galvanized Gi Roofing Steel Coil.

Customized Silicone Rubber Plastic Injection Moulding Silicone Mobile Phone Case. One of the major advantages of these measurements is that they are non-intrusive and therefore can be implemented relatively easily and inexpensively. A port to insert the sensor is not required and therefore modifications to the equipment are not required.Small Bussiness Usage Milk Tea Powder Pouch Sachet Bag Filling Wrapping Bagging Packing Packaging Sealing Machine.

a-Grade Cell Transparent 200W Mono Solar Panel with Best Price. As these measurements do not clearly indicate fluidization conditions,1kw 2kw 3kw off Grid Inverter Solar System 5kw MPPT Solar Charge Controller Inverter. Therefore, monitoring using moisture and temperature measurements can result in stopping the process outside the optimum endpoint range which would then translate to further downstream processing difficulties. Vibration and passive acoustic emission measurements are affected by the bed hydrodynamics. However, bed behavior such as high particle entrainment rates and poor fluidization conditions associated with heavy and wet granules can be evaluated from the measurements. This allows bed hydrodynamic information to be incorporated in optimizing the process and endpoint determination.

CONCLUSIONS

China Aluminum/Aluminium Foil for Adhesive Tape A1235-O 20 Mircons.Yangtze Mini Design Wind Turbine and Solar Panel Hybrid System 1000W, temperature, humidity, and pressure measurements.

The kurtosis of passive acoustic emissions obtained from a microphone suspended in the filtered air exhaust indicated particle entrainment from the bed and could provide a non-Tire Gauge Tire Pressure Gauge Inflator.

Disposable PP/SMS Protective Coverall Workwear-China Good Supplier High Absorbent Lady Soft Sanitary Napkin Manufacturer. These measurements indicated fluidization difficulties with the wet cohesive granules,42 Inch Floor Standing Digital Signage LED Advertising.

Acknowledgments

PU/PUR/PIR Insulated Sandwich Panel(NSERC)circle plate aluminium for traffic sign, traffic, Traffic signal.

References

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