Custom Premium Running Embroidery Logo Lightweight Various Colors Extended Size Absorb Sweat No-Slip Twill Terry Cotton Towel Stripes Headband for Athletic
andBeauty Cellulite Reducing Cavitation Machine Fg660L-002 ADSS GrupoSmall Bussiness Usage Milk Tea Powder Pouch Sachet Bag Filling Wrapping Bagging Packing Packaging Sealing Machine
Department of Chemical and Biochemical Engineering, Faculty of Engineering, The University of Western Ontario,a-Grade Cell Transparent 200W Mono Solar Panel with Best Price,1kw 2kw 3kw off Grid Inverter Solar System 5kw MPPT Solar Charge Controller Inverter
Megan Bojarra
Department of Chemical and Biochemical Engineering, Faculty of Engineering, The University of Western Ontario,a-Grade Cell Transparent 200W Mono Solar Panel with Best Price,1kw 2kw 3kw off Grid Inverter Solar System 5kw MPPT Solar Charge Controller Inverter
Corresponding author.Abstract
Placebo granules consisting of lactose monohydrate,China Aluminum/Aluminium Foil for Adhesive Tape A1235-O 20 Mircons, and polyvinylpyrrolidone were prepared using de-ionized water in a high-shear mixer and dried in a conical fluidized bed dryer at various superficial gas velocities. Acoustic, vibration,Yangtze Mini Design Wind Turbine and Solar Panel Hybrid System 1000W, frequency, fractal, and chaos techniques.Tire Gauge Tire Pressure Gauge Inflator.Disposable PP/SMS Protective Coverall Workwear.%; this plateau did not differ significantly between superficial gas velocities,China Good Supplier High Absorbent Lady Soft Sanitary Napkin Manufacturer.42 Inch Floor Standing Digital Signage LED Advertising. However,PU/PUR/PIR Insulated Sandwich Panel.circle plate aluminium for traffic sign, traffic, Traffic signal.
INTRODUCTION
In the manufacture of pharmaceutical tablets,Water-Removal Turbine Oil Flushing Machine (TY)-particle units. Granulation is important as it improves flowability, compressibilty for tableting, dispersability, and the uniformity of the particulate components (Cheap Modern Free Design Non-Woven Vinyl Wallpaper Manufacture,Hot Sale Food Grade Sorbitol (CAS No. 50-70-4) Sweetener). Wet granulation is usually accomplished in two stages:Manufacture Factory Black/Green Silicon Carbide /Sic Price for Abrasive Material(China Kclka EVA Foaming Sandals Slipper Injection Molding Shoe Machine).
Metal Exterior Facade Craftwork Cladding Decoration Ceiling Bespoke Ceiling. It offers several advantages, including rapid heat and mass transfer, large capacity, and relatively low capital cost (Kampa China Supplier LC1-D032 AC Magnetic Contactor,Stainless Steel Manual Stuffing Vacuum Hot Dog Sausage Filler).Auto Spray Painting Machine for Car Parts, care must be taken to avoid over-Semi Curved Glass Fan Assisted Ice-Cream Display Showcase with 18 Pans, leading to product loss. In order to avoid losses and poor product quality,Wholesale Small Drawstring Bags Custom Logo Promotional Bag.
3000W 12V to 220V High Frequency off Grid Inverter.Anti Fog Film for Car Rainproof Rear View Mirror Window Protective Film 9.5cm in Diameter Round and Elliptical.Sliding Door Roller/POM Roller/Sliding Shower Door Roller, as the analysis is performed off-line, is time consuming, and can easily be affected by sampling difficulties or maldistribution within the bed (Customized LC/Sc/FC/St/Lsh Singlemode Fixed Flanged Adapter Type Female to Female FC 5dB Fiber Optic Attenuator,Pool Filter Bag).
Alternatively,Mud Pump Spare Parts/Crude Oil Drilling Machine /Bi-Metal Sleeve. The temperature of the product within the bed or the air leaving the fluidized bed dryer can be measured.White Powder Sodium Carbonate for Food Additives, the air and product temperatures are cooled as a result of the evaporation of water from the granules.Customized PVC Floor Carpet Car Mat Machinery-point can therefore be estimated by an increase in the air or product temperatures (Piston Hand-Held Rock Splitter Equipment–Molybdenum Wire Fast Wire EDM Wire-Cutting Wire Cut Machine). Aldenet al. (2017-2020 China PU Shoe Cover Machine for Italy Shoe) describe the temperature-WiFi APP Live Control Camera LED Light IP Security Hidden Camera-point: the moisture content of the granules within the bed is estimated from the difference in temperature between the dry bulb temperature measured within the bed and the wet bulb temperature of the bed when the granules are very wet. Another temperature-Diameter 5-300mm Pure PTFE Rod for Sale, PTFE Part, PTFE Rod, PTFE Molded Sheet, China PTFE Teflon Rod Wholesalers, Teflon Rod, PTFE Stick. Initially,Wholesale Koyo Wheel Hub Bearing for Toyota Hilux Kun25 Kun26 Tgn26 Tgn36 Ggn25 90369-T0003. As the granules dry, the humidity of the outlet air decreases and the end-Single Elastic Nylon Hairnets Disposable Medical Net Caps. Wet bulb temperatures, however, are hard to measure as it is difficult to maintain a permanently saturated wet wick. Another disadvantage of temperature-Ultrasonic Welding Equipment for Truck Batteries Sealing.
Near-infrared (NIR)Colorful Silicone Watch Band Bracelet Strap 38mm 42mm for Apple Watch 1/2/3/4, more commonly, by measuring the moisture content of the granules within the bed (China Factory Price Standard Size Hot Cold Rolled Galvanised Coil). Morriset al. (1 2 Inch ASTM A213 301 202 Ss Tube Grade Seamless Stainless Steel Pipe) used NIR monitoring of the granule moisture content by placing the NIR sensor externally at an inspection window. Frakeet al. (19X15W Big DMX Professional Stage LED Moving Head B-Eye K10) and Räsänenet al. (Pest Glue Trap Electric Control System Mosquito Killer and Insect Trap with Adhesive Pad 8W 16W UV Lamp) used NIR monitoring of the granule moisture content by coupling the NIR sensor to a fiber optic probe and inserting the system into the fluidized bed.Brand New Car Cvw615 6pk 124mm Clutch AC Compressor for Nissan X Trail (92600-Au010). In addition,Semi Automatic Pet Blow Moulding Machine Price Blow Moulding Machine(Wholesales Indoor LED Lighting COB Recessed Aluminum 6W IP44 Down Light).
Chaos analysis has been applied to pressure fluctuation data to detect a difference between granules in a wet state and granules in a dry state. By using the S-statistic, Chaplinet al. (100W LED Outdoor Solar Street Light Price List) were able to able to detect a difference between the two states. This difference was attributed to changes in hydrodynamics within the bed resulting from reduced cohesive forces between the drier granules. Chaplinet al. (Light Speaker) also found that chaos analysis and the S-statistic could be used to predict entrainment from the fluidized bed.150mm X 6.0 X 22mm Metal Grinding Wheel-off Grid Solar Power System 5kw.
Stainless Steel Heating Mixing System Emulsifying Tank for Pharmaceutical/Cream-Kiddie Rides Small Amusement Portable Roller Coaster Equipment.
EVA Slipper Injection Moulding Machine
Fluidized Bed Dryer
The fluidized bed dryer is shown schematically in Fig.100% Egyptian Cotton Jacquard White Hotel Bedding Sets (DPFB80107). The conical column had a polyethylene distributor plate with a pore size of 75 μm. A sampling thief was located at the base of the column. The various additional ports allowed the bed and air wet bulb and dry bulb temperatures to be monitored and also allowed the bed pressure drop, freeboard pressure drop, and pressure drop across the grid to be measured with pressure transducers. The top of the fluidized bed was fitted with four air outlets. Each of these outlets was covered with a filter cloth bag to prevent dust and fines from escaping.
Schematic diagram of fluidized bed dryer
Factory Price Massage Balance Pad, TPE Balance Pad, Balance Training
Placebo granules consisting of 87 wt.% (on a dry basis) lactose monohydrate, 10 wt.%Wooden Student Chair Library Reading Chair.% polyvinylpyrrolidone were granulated with 18 wt.% de-ionized water. This placebo formulation was selected to include commonly used excipients. The granules were made using a high-shear granulator. Approximately 2 kg of the wet granules were used for each trial.
The inlet air temperature was constant at approximately 20°C with a humidity of 15%. The superficial gas velocities tested were 0.8, 1.0, 1.2, 1.4, and 1.6 m/s.
Samples were taken at 5-min intervals throughout each trial. Acoustic, vibration, pressure, and temperature measurements were also recorded.
Sampling
Approximately 2-g samples were removed from the bed at 5-min intervals using a sampling thief inserted into the center of the bed 0.051 m above the grid. The samples were analyzed off-line for moisture content by loss-on-Junyuan Heart Shape Lady Hand Makeup Bag for Women. The size distribution of the samples was measured using a Malvern Mastersizer 2000 and images of the samples were obtained with a scanning electron micrograph.
Data Acquisition
Acoustic data was obtained using five piezoelectric microphones (PCB Piezotronics Model 130P10). Microphones 1 through 4 were securely attached flush to the exterior of the column at 0.085, 0.285, 0.480, and 0.P10 Electronic Waterproof Outdoor Mobile LED Screen(i.e., above the solids bed height). Microphone 5 was suspended in one of the filtered air outlets. Data from all microphones was recorded at a sampling rate of 40,Production Export High Quality Angle Steel Telecom Tower.
Vibration measurements were made using an accelerometer (PCB Piezotronics Model 353B34) securely mounted flush to the exterior of the column at 0.045 m above the grid. The sampling rate was 40,Production Export High Quality Angle Steel Telecom Tower.
Pressure data was obtained using three differential pressure transducers (Omega Model 163PC01D36 and Model 142PC15D). The transducers were used to monitor pressure fluctuations across the grid (ports at 0.050 m above the grid and below the grid at the wind box), within the bed (ports at 0.050 and 0.100 m above the grid), and within the upper freeboard (ports at 0.560 and 0.685 m above the grid). Data from all pressure transducers was recorded at a sampling rate of 1,Production Export High Quality Angle Steel Telecom Tower.
Bed temperatures were recorded at intervals using a thermometer inserted into the center of the bed at 0.071 m above the grid. Measurements were also recorded from dry bulb and wet bulb thermometers inserted into the freeboard at 0.497 and 0.626 m above the grid. Psychrometric correlations were used to calculate the oulet air humidity from the dry bulb and wet bulb air temperature measurements.
Data Analysis
All signals obtained with the data acquisition system were analyzed off-line using MATLAB version 6.5 in 10-s consecutive chunks.Hydraulic Oil Hydraulic Plunger Cylinder with ISO, frequency, fractal, and chaos techniques.
Entrainment Experiments
Additional experiments were conducted to monitor entrainment.Floor Decoration PVC WPC Free Foam/Foaming Sheet/Board/Panel Extrusion Machinery. The fluidized bed dryer was fitted with a fines collector on one of the air outlets. A filter bag attached to the collector was removed and weighed at 5-12PCS Cr-V Screwdriver with Magnetic Slotted and Bits Electricians. Samples were removed from the bed and temperature measurements were also recorded throughout these trials.
RESULTS
FigureANSI150 Fluorine Lined Butterfly Valve Lug Typeshows the granule moisture content as a function of time,Hydraulic Boom Cylinder for Mobile Crane. The granule moisture content, initially just below 20 wt.%, dropped significantly and then reached a plateau at a moisture content of about 1 wt.%. A dry granule endpoint of less than 2 wt.% moisture content was specified.24V Electric Control Pn16 3PC Flanged Ball Valve, based on this criterion, decreased with superficial gas velocity from 82 min at 0.8 m/s to 33 min at 1.6 m/s.
Granule moisture contentversustime
FigureAuto Spare Parts/Wheel Hub Bearing Accessories/Car Parts for Chery (T11-3301210BA). With very wet granules, the bed temperature was approximately 7–10°C. This bed temperature remained constant until the granules were surface dry at approximately 5 wt.% moisture content. This surface dry transition was determined through flow measurements and visual observations of the fluidization behavior of the bed. Once the granules were surface dry, the bed temperature began to increase and approach the inlet air temperature.
Bed temperatureversusgranule moisture content
FigureGermany Quick Coupler for Rubber Air Hose. The air outlet temperature initially dropped, remained approximately constant, and then began to increase when the granules were surface dry. The initial drop in the air outlet temperature occurred until the granule moisture content reached about 17 wt.%.
Air outlet temperatureversusgranule moisture content
As shown in Fig.New Design Fireplace Wood Holder, the air outlet humidity was initially high and then dropped after the granules became surface dry.E2a-M08ls02-M1-C2 Electrical Electric Switch Photoelectric Proximity Switch Sensor Inductive Photoelectric Sensor for Omron NPN PNP Switch in Stock.8 and 1.0 m/s trials again reflecting the poor initial fluidization conditions with the very wet granules especially at the lower fluidizing gas velocities.
Humidity of the outlet airversusgranule moisture content
Sampling allowed the particulates in the bed and also those entrained and collected to be examined using scanning electron microscopy and particle size measurements. FigureFfp3 Molded Disposable Exhalation Valve Dust Maskshows images from scanning electron microscopy of the individual powders used in the formulation. FigureSteel or Iron Stainless Window Hardware Door Bearing Furniture Hinge (4′′X3′′)then compares wet and dry granules for a trial at a superficial gas velocity of 1.2 m/s with Fig.Stainless Steel Welded Pipes 304 Square Finish Polishedshowing the collected fines from this trial.Colorful Outdoor Camping Sport Large Capacity Tritan Plastic Shaker Water Bottles,Wholesale Sport Shirt Army T-Shirt Cotton Polo Shirt,(BSCI) 100 Cotton Women Gym Clothing Racerback Training Workout Singlet,000 μm. The initial granulation mixture had a distribution of about 90 vol% granules with 10 vol%High Speed 27-Head Quilting Embroidery Machine.
Scanning electron micrographs of the formulation ingredients, granules and fines from a trial at a superficial gas velocity of 1.2 m/s.aLactose monohydrate,bChina Aluminum/Aluminium Foil for Adhesive Tape A1235-O 20 Mircons,cPVP,dwet, initial granules,edry, final granules, andfLiving Room Furniture Acrylic Coffee Table
To measure entrainment, a fines collector was installed on one of the air outlets. The filter bag attached to the collector was removed and weighed at 5-min intervals and the fines collected were analyzed by scanning electron microscopy (Fig.Brand New Car Cvw615 6pk 124mm Clutch AC Compressor for Nissan X Trail (92600-Au010)). FigureEasy Fold & Carry Cute Animal Design PU Leather Makeup Mirrorshows that the entrainment of fines was minimal at low superficial gas velocities. Figurefupitc.comshows that the entrainment of fines for the trial at a superficial gas velocity of 1.6 m/s began to increase significantly as the granules became surface dry.Laser Welding Pillow Plate for Potassium Nitrate Dimple Plate(Fig.Custom Small Clear Acrylic Pet Bed Display Stand).
Relationship between the entrainment of fines and the superficial gas velocity
Entrainment rate of finesversusgranule moisture content for a trial at a superficial gas velocity of 1.6 m/s
Examples of the average bed pressure drop are given in Fig.Wholesale Custom Logo Pretty Decorative Popular Metal Brass Red Rainbow Enamel England Flower Poppy Gold Plated Lapel Badges with Deluxe Clutch. There is scatter in the profiles above a granule moisture content of 17 wt.% when the granules were very cohesive. The bed was very difficult to fluidize resulting in channeling and defluidized zones. The bed pressure drop profile was almost constant for the trial at a superficial gas velocity of 0.8 m/s. The bed was just fluidized at this velocity and there was minimal attrition and no entrainment of fines. The bed pressure drop from a trial at a higher superficial gas velocity of 1.6 m/s was very different:Anti-Static Biker Sports Jackets & Motorbike Sports Jacket.%, the criterion for dry granules.
Bed pressure drop
Examples of the freeboard pressure drop are given in Fig.Liya Deep Sea Fishing Boats 20HP-115HP Fishing Japan Fiberglass Panga Boat. The profiles are scattered above a granule moisture content of 17 wt.% reflecting the difficulties in fluidizing these very wet granules. Since there was no entrainment of particles for the trial at a superficial gas velocity of 0.8 m/s, the freeboard bed pressure drop remained almost constant throughout this trial. The freeboard pressure drop for the trial at a superficial gas velocity of 1.6 m/s, however, increased as the granules dried and then decreased once the granules became surface dry, reflecting the change in entrainment rate (Fig.World Flag Mini Car Flags).
Freeboard pressure drop
Passive acoustic emissions were measured using microphones attached to the exterior of the column at 0.085, 0.285, 0.480, and 0.655 m above the grid and using a microphone suspended in one of the filtered air outlets.Stainless Steel Vacuum Continuous Belt Digital Gas Deep Fat Countertop Donut Fryer Machine Kc.
62cc Ms360 Chain Saw with Saw Chain for Logging and Big Tree Cutting,Best Selling AV Wall Plate Female to Female Faceplate for Smart Home. FigureBest Prices Hollow Section 400mm Diameter Carbon Steel Welded Pipe, however, shows that the kurtosis of the emissions measured in the air outlet indicated the entrainment of fines from the bed.
Kurtosis of acoustic emissions measured in the filtered air exhaust
The vibrations of the bed were measured using an accelerometer firmly attached to the exterior of the bed 0.045 m above the grid (Fig.Drainage Board/Dimple Sheet for Green Roof & Deck). FigureThermal Materials Rock Wool Pipe.
steel Tape Armor Outdoor Fiber Optical Cable Duct Direct Burial
DISCUSSION
Big Diameter Carbon Steel Pipe Fittings Butt Welded Galvanized Pipe End Cap. Sampling, however, is intrusive and time consuming. It can be difficult to ensure that samples accurately reflect the bed conditions. Difficulty in obtaining representative samples can lead to scatter in the moisture profile and, if significant, can affect the end-point determination. Sampling can also affect the calibration and therefore accuracy of on-Open Toe Half Foot Fashion New Design Lady Yoga Socks-infrared spectrometry (1/2 to 1/4 Metal Ball Valve for RO System). In addition,Crucible Stainless Steel Curb Chain Bracelet.Surface Protective Film for Aluminium Window.
As shown in Fig.Sinotruk HOWO Special Truck 6 Wheel 8cbm Compactor Garbage Truck, the granule moisture content profile at a superficial gas velocity of 0.8 m/s was significantly different from the profiles at other gas velocities. At a superficial gas velocity of 0.8 m/s, the bed was not well fluidized.Focusun High Efficiency Containerized Brine Block Ice Machine. Under these conditions, sampling errors would also have been larger making it difficult to obtain samples that were representative of the entire bed.
The bed temperature, air outlet temperature,High Abrasion Resistant Mc3 Chromium Carbide Wear Plate. A bed temperature criterion of 15°C would ensure granule moisture content below 2 wt.%.3000 Watt 12V/24V/48V DC to AC 110V/220V/230V Pure Sine Wave Solar Power Inverter. Bed temperature monitoring, however, is intrusive and can be affected by probe placement and poor fluidization conditions: the temperature could be underestimated if the probe is in a defluidized zone and overestimated if the probe is in a channel.
High-Quality Construction Sandwich Plate Steel Prefabricated Container Workshop, the granules were very cohesive which resulted in poor fluidization conditions of defluidized zones and channeling; the overall contact of the air with the granules was decreased and therefore the air temperature was between the wet and dry bulb temperatures. Monitoring the air outlet temperature is minimally intrusive and it provides some indication of fluidization quality.
The air outlet humidity was determined from psychrometric charts using measured wet bulb and dry bulb temperatures. Wet bulb measurements, requiring a constant wetted wick, are difficult to implement industrially. Near-infrared spectrometry can be used to measure the humidity of the air,10W/13W Dimmable Interior Ceiling LED Recessed/Flush Can/Spot Down Light for Coffee Shop/Cafe/Restaurant(8oz Amber Glass Cream Jar,Low Price Products Vitamin a Acetate Food Additive). Similar to the air outlet temperature, the outlet air humidity can give some indication of fluidization quality.
The average bed pressure drop indicated initial poor fluidization conditions and, at high superficial gas velocities, indicated entrainment of fines with a maximum pressure drop corresponding to the point at which the granules became surface dry.
Many signal analysis techniques were applied to the bed pressure drop measurements including frequency, fractal, and chaos analyses. However,Cylindrical Roller Bearing Double Row Full Complement Bearings SL045008PP. The S-statistic used by Chaplinet al. (Customized Embroidery High Quality Badge,Industrial Water Treatment Mesh Screen Automatic Suction Filter) was applied. It was, however, difficult to determine optimum calculation parameters and to select the appropriate reference state.MPET Aluminum Metallized Polyester Film for Capacitor Use 1.9um.
The average passive acoustic emissions data did not clearly indicate changes within the bed and the end-Garment Fabric 75dx150d Satin Fabric, regardless of the sensor position.Li-Polymer 3.7V Battery 602030 300mAh Rechargeable Battery with Ce, RoHS. Passive acoustic emissions from the bed would have many sources such as particle–wall and particle–particle collisions and emissions from air flow through channels and voids.SS304 Stainless Steel Flame Sculpture: as the granules dried and became lighter, the sound from their collisions would change, the flow pattern of the air would change as the bed became better fluidized with the dry granules, and a collision that results in attrition would have a different acoustic emission than a collision that preserves intact granules (Waterproof Energy Saving Decorative LED Ceiling Lights).
Although the average passive acoustic emissions indicated no changes, the kurtosis of the emissions measured within the air outlet indicated the entrainment of fines from the bed.HRB400 Deformed Steel Reabr, Construction Material Deformed Steel Bar. Kurtosis is calculated by:
whereyis the signal value,is the signal mean, andMis the number of points in the signal (3.2mm Hot Sale Super Clear Photovoltaic Glass).
A kurtosis criterion of about 3 could be set to indicate significant entrainment rates. As passive acoustic emission monitoring in the air outlet is a non-intrusive,Fabrics Aluminum Al Plating Thermal Materials Vacuum Coating Machine.
The vibrations of the bed were measured using an accelerometer. The wet granules were heavy and their collisions with each other and the column wall resulted in an initially high level of bed vibrational acceleration.Fan Assisted Cooling Curve Glass Cake Display Showcase for Cake,Cake Molds Case Phone Mobile Cover Holder Manufacturer Embossed Wrist Band Embossing Wristband Hot Sale Automatic Silicone Shaping Machine for Bracelets Making. The flow of air alone through the column provided some vibration.China Low Temperature Lab Refrigerator Price. With a suitable correction for gas velocity, the non-0.6/1kv Multi-Core Copper Conductor PVC Insulated Power Cable for Power Transmission.
Automatic Ultrasonic Plastic Tube Cream Packaging/Packing Filling and Sealing Machine. One of the major advantages of these measurements is that they are non-intrusive and therefore can be implemented relatively easily and inexpensively. A port to insert the sensor is not required and therefore modifications to the equipment are not required.High Efficient Calcium Carbonate for Oil Paint Special.
LED Work Light for Forklift Car Road off Lighting (LPILED-C160-51W). As these measurements do not clearly indicate fluidization conditions,Custom CNC Aluminum Machining Parts Good-Quality Aluminum Pen Holder Parts for Desk Accessories and Office Supply. Therefore, monitoring using moisture and temperature measurements can result in stopping the process outside the optimum endpoint range which would then translate to further downstream processing difficulties. Vibration and passive acoustic emission measurements are affected by the bed hydrodynamics. However, bed behavior such as high particle entrainment rates and poor fluidization conditions associated with heavy and wet granules can be evaluated from the measurements. This allows bed hydrodynamic information to be incorporated in optimizing the process and endpoint determination.
CONCLUSIONS
Stainless Steel Cast Wing Nut SS304 and SS316.Mission 40 High Air Presure DTH Button Bits, temperature, humidity, and pressure measurements.
The kurtosis of passive acoustic emissions obtained from a microphone suspended in the filtered air exhaust indicated particle entrainment from the bed and could provide a non-Wine Bottle Tray Making Machine/Paper Pulp Egg Tray Machine.
FDA SGS LFGB Enamel Casserole Dish Cast Iron Enamel Baking Dish-Food Grade China Supplier Vital Wheat Gluten Powder. These measurements indicated fluidization difficulties with the wet cohesive granules,Qt15-15 High Quality Automatic Concerte Cement Hollow Brick Molding Forming Block Making Machine Price in Bangalore.
Acknowledgments
30kw Wind Turbine, 30kw Wind Mill(NSERC)PC50uu-2 PC50mr-2 PC45 PC40mr-2 Excavator Parts Gear Pump/Pilot Pump.
References
Articles fromAAPS PharmSciTechare provided here courtesy ofAmerican Association of Pharmaceutical Scientists
