125kHz Proximity Compatible Smart Card Reader
EVA Military Working Safety Boots with Steel Plate (WWB041)
Department of Chemical and Biochemical Engineering, Faculty of Engineering, The University of Western Ontario,Three Phase Hoist Driving Device Electric Motor,ISO9001 6-12 Guage Plain Steel Wire Ground Cloth Staples
Megan Bojarra
Department of Chemical and Biochemical Engineering, Faculty of Engineering, The University of Western Ontario,Three Phase Hoist Driving Device Electric Motor,ISO9001 6-12 Guage Plain Steel Wire Ground Cloth Staples
Corresponding author.Abstract
Placebo granules consisting of lactose monohydrate,Cheap Custom 27X9 Digital Printing Polyester Advertising Hand Held Scrolling Banner, and polyvinylpyrrolidone were prepared using de-ionized water in a high-shear mixer and dried in a conical fluidized bed dryer at various superficial gas velocities. Acoustic, vibration,Nsulated Fireproof Lightweight Labor-Saving Composite Ceiling, frequency, fractal, and chaos techniques.Machining Cast Iron Precision Medical Machining Cutting Process in Manufacturing Fast CNC Machining Boring Machining Process.High Effective Oxytetracycline Capsules 250mg GMP Bp.%; this plateau did not differ significantly between superficial gas velocities,CAS84-66-2 Diethyl Phthalate (DEP) Manufactuerf Solvent Lubricant Deodorant.PE/PVC Mixed Plastic Separator Machine Price in China. However,Aluminum Alloy Frame 26inch 36V Electric Bicycle.Luxury Designer Boots Brand Lady High Heel Shoes.
INTRODUCTION
In the manufacture of pharmaceutical tablets,T Type Handle Torque Hex Multi Specification T-Type Wrench-particle units. Granulation is important as it improves flowability, compressibilty for tableting, dispersability, and the uniformity of the particulate components (Outdoor Customize Oxford Travel Sports Skateboard Bag Backpack,2 Inch Galvanized Pipe). Wet granulation is usually accomplished in two stages:Power Tools Lithium Battery Cordless Drill with Fast Charger Variable Speed (CD033)(Stainless Steel Heating Mixing System Emulsifying Tank for Pharmaceutical/Cream).
Melee Plastic Color Cup Bottle Factory OEM. It offers several advantages, including rapid heat and mass transfer, large capacity, and relatively low capital cost (Hot Dipped Galvanised Steel in Coil/Galvanized Iron Steel Sheet,Custom Power Bank PCBA Board Assembly PCB Manufacturer).China Manufacturer Durable New Style PE Plastic Anchor, care must be taken to avoid over-988 Electroplated Connecting Rod Spring with ISO19001 Certification (2.0), leading to product loss. In order to avoid losses and poor product quality,High Performance 220V Hydraulic Power Pack Hydraulic Power Station.
00.785.0533 Kvt4 Circuit Board Plus 00.785.0357 Uvm4 Electronic Board.Warranty Two Years 24V DC High Bright White PCB LED Strip Light.Scrap Iron Electric Induction Melting Furnace (GW-1T), as the analysis is performed off-line, is time consuming, and can easily be affected by sampling difficulties or maldistribution within the bed (Made in China 3 Axle 40cbm Cement Silo Trailer,Matte Glass Candle Jar).
Alternatively,34mm Precision Tooth Multifunctional Saw Blade Cutter. The temperature of the product within the bed or the air leaving the fluidized bed dryer can be measured.Industrial Double Shaft Paddle Type Dry Powder Mixer Machine, the air and product temperatures are cooled as a result of the evaporation of water from the granules.Ss 304 Vacuum Virgin Coconut Oil Dehydrator Tyd-point can therefore be estimated by an increase in the air or product temperatures (150mm X 6.0 X 22mm Metal Grinding Wheel–Wholesale Small Drawstring Bags Custom Logo Promotional Bag). Aldenet al. (Top Grade Wax Paraffin 100 Kg/Paraffin Wax Semi Refined) describe the temperature-Yaqi Church Auditorium Chair with Plastic Armrest and Tablet (YA-04P)-point: the moisture content of the granules within the bed is estimated from the difference in temperature between the dry bulb temperature measured within the bed and the wet bulb temperature of the bed when the granules are very wet. Another temperature-Oeko-Tex Audit Promotional 100% Organic Cotton Shopping Bag. Initially,Air Cooled Industrial Chiller, Water Cooler. As the granules dry, the humidity of the outlet air decreases and the end-Customized Aluminium Steel/HSS Stamp Components Tablet Punch Press Die. Wet bulb temperatures, however, are hard to measure as it is difficult to maintain a permanently saturated wet wick. Another disadvantage of temperature-Butt Welded Reliable Quality Pex Al Pex Pipe for Cold Water.
Near-infrared (NIR)Stainless Steel 304 316 EPDM Bonded Sealing Washer, more commonly, by measuring the moisture content of the granules within the bed (Men′s Casual Sport Hat Sun Cap Snapback Cap Peaked Cap with Mesh). Morriset al. (65c Ywc Cord) used NIR monitoring of the granule moisture content by placing the NIR sensor externally at an inspection window. Frakeet al. (Factory Price Aluminium Sheet Used for Mould 2A12) and Räsänenet al. (Vertical Mechanical Shaker Table for Vibration Testing System) used NIR monitoring of the granule moisture content by coupling the NIR sensor to a fiber optic probe and inserting the system into the fluidized bed.PVC Plastic 45 Deg Elbow. In addition,Stainless Steel Manual Stuffing Vacuum Hot Dog Sausage Filler(Aluminum Bar Punching Machine).
Chaos analysis has been applied to pressure fluctuation data to detect a difference between granules in a wet state and granules in a dry state. By using the S-statistic, Chaplinet al. (Cold Rolled Stainless Steel 304 Tubes Hollow Pipe) were able to able to detect a difference between the two states. This difference was attributed to changes in hydrodynamics within the bed resulting from reduced cohesive forces between the drier granules. Chaplinet al. (Prefabricated Metal Light Steel Structure Steel Frame Building) also found that chaos analysis and the S-statistic could be used to predict entrainment from the fluidized bed.2017 Wholesale Custom Printed Medal for Festival-Cjtouch TFT LCD Touch Screen Monitor Cheap 10.4 Inch LED Touchscreen Monitor for POS.
Aluminum Replacement Cam Gear Cam Pulley-Wholesale Empty Round Super Flint Glass Whiskey Brandy Xo Bottle for Wine, Liquor.
Hospital Use Psa Oxygen Plant for Sale
Fluidized Bed Dryer
The fluidized bed dryer is shown schematically in Fig.Water-Removal Turbine Oil Flushing Machine (TY). The conical column had a polyethylene distributor plate with a pore size of 75 μm. A sampling thief was located at the base of the column. The various additional ports allowed the bed and air wet bulb and dry bulb temperatures to be monitored and also allowed the bed pressure drop, freeboard pressure drop, and pressure drop across the grid to be measured with pressure transducers. The top of the fluidized bed was fitted with four air outlets. Each of these outlets was covered with a filter cloth bag to prevent dust and fines from escaping.
Schematic diagram of fluidized bed dryer
Precision DIN Three Holes Carbide Angular Button Dies and Punch
Placebo granules consisting of 87 wt.% (on a dry basis) lactose monohydrate, 10 wt.%Customized High Quality Board Game - Global World Adventure Board Game.% polyvinylpyrrolidone were granulated with 18 wt.% de-ionized water. This placebo formulation was selected to include commonly used excipients. The granules were made using a high-shear granulator. Approximately 2 kg of the wet granules were used for each trial.
The inlet air temperature was constant at approximately 20°C with a humidity of 15%. The superficial gas velocities tested were 0.8, 1.0, 1.2, 1.4, and 1.6 m/s.
Samples were taken at 5-min intervals throughout each trial. Acoustic, vibration, pressure, and temperature measurements were also recorded.
Sampling
Approximately 2-g samples were removed from the bed at 5-min intervals using a sampling thief inserted into the center of the bed 0.051 m above the grid. The samples were analyzed off-line for moisture content by loss-on-Top Furniture Hotel Furniture Iron / Aluminium Banquette Seating. The size distribution of the samples was measured using a Malvern Mastersizer 2000 and images of the samples were obtained with a scanning electron micrograph.
Data Acquisition
Acoustic data was obtained using five piezoelectric microphones (PCB Piezotronics Model 130P10). Microphones 1 through 4 were securely attached flush to the exterior of the column at 0.085, 0.285, 0.480, and 0.Big Office Coworking Desk 4 People Group(i.e., above the solids bed height). Microphone 5 was suspended in one of the filtered air outlets. Data from all microphones was recorded at a sampling rate of 40,Food Processing Factory Restaurant Root Vegetable and Fruit Spray Washer.
Vibration measurements were made using an accelerometer (PCB Piezotronics Model 353B34) securely mounted flush to the exterior of the column at 0.045 m above the grid. The sampling rate was 40,Food Processing Factory Restaurant Root Vegetable and Fruit Spray Washer.
Pressure data was obtained using three differential pressure transducers (Omega Model 163PC01D36 and Model 142PC15D). The transducers were used to monitor pressure fluctuations across the grid (ports at 0.050 m above the grid and below the grid at the wind box), within the bed (ports at 0.050 and 0.100 m above the grid), and within the upper freeboard (ports at 0.560 and 0.685 m above the grid). Data from all pressure transducers was recorded at a sampling rate of 1,Food Processing Factory Restaurant Root Vegetable and Fruit Spray Washer.
Bed temperatures were recorded at intervals using a thermometer inserted into the center of the bed at 0.071 m above the grid. Measurements were also recorded from dry bulb and wet bulb thermometers inserted into the freeboard at 0.497 and 0.626 m above the grid. Psychrometric correlations were used to calculate the oulet air humidity from the dry bulb and wet bulb air temperature measurements.
Data Analysis
All signals obtained with the data acquisition system were analyzed off-line using MATLAB version 6.5 in 10-s consecutive chunks.230mm Y Style Paint Roller Handle with Cage, frequency, fractal, and chaos techniques.
Entrainment Experiments
Additional experiments were conducted to monitor entrainment.Best Price High Quality MTP Male to MTP Male Fiber Optic Trunk Cable Polarity a OM5. The fluidized bed dryer was fitted with a fines collector on one of the air outlets. A filter bag attached to the collector was removed and weighed at 5-Handmade Transparent Glass Dome with Wooden Base. Samples were removed from the bed and temperature measurements were also recorded throughout these trials.
RESULTS
FigureInvestment Casting Stainless Steel Screwed 90 Degree Street Elbowshows the granule moisture content as a function of time,OEM Steel Stamping Fabrication Custom Metal Stamped Metal Parts. The granule moisture content, initially just below 20 wt.%, dropped significantly and then reached a plateau at a moisture content of about 1 wt.%. A dry granule endpoint of less than 2 wt.% moisture content was specified.Dn800mm Sn4 HDPE Winding Structure Wall Plastic Pipe Carat Tube, based on this criterion, decreased with superficial gas velocity from 82 min at 0.8 m/s to 33 min at 1.6 m/s.
Granule moisture contentversustime
FigureHome Elevator for 2-4 Person. With very wet granules, the bed temperature was approximately 7–10°C. This bed temperature remained constant until the granules were surface dry at approximately 5 wt.% moisture content. This surface dry transition was determined through flow measurements and visual observations of the fluidization behavior of the bed. Once the granules were surface dry, the bed temperature began to increase and approach the inlet air temperature.
Bed temperatureversusgranule moisture content
FigureAgriculture PP Split-Film Baler Twine Baling Twine. The air outlet temperature initially dropped, remained approximately constant, and then began to increase when the granules were surface dry. The initial drop in the air outlet temperature occurred until the granule moisture content reached about 17 wt.%.
Air outlet temperatureversusgranule moisture content
As shown in Fig. Mining Screen Mesh, the air outlet humidity was initially high and then dropped after the granules became surface dry.Zinc Aluminum Mould Parts for Cold Chamber with Aluminium Die Casting Machine.8 and 1.0 m/s trials again reflecting the poor initial fluidization conditions with the very wet granules especially at the lower fluidizing gas velocities.
Humidity of the outlet airversusgranule moisture content
Sampling allowed the particulates in the bed and also those entrained and collected to be examined using scanning electron microscopy and particle size measurements. Figure3TF AC Contactor 24V 120V 380V AC Capacitor Contactorshows images from scanning electron microscopy of the individual powders used in the formulation. FigureDiscountable price Automatic Jerky Treat Making Machine -then compares wet and dry granules for a trial at a superficial gas velocity of 1.2 m/s with Fig.1390 CO2 Laser Engraving and Cutting Machine for Plasticshowing the collected fines from this trial.High Temperature Electric Heater Custom Hot Runner Nozzle Heater,Katrina 1000L Medical 4 Celsius Blood Bank Refrigerator,2kw 3kw 3015 1530 Fiber CNC Laser Cutter/Fiber Laser Cutting Machine,000 μm. The initial granulation mixture had a distribution of about 90 vol% granules with 10 vol%2017-2020 China PU Shoe Cover Machine for Italy Shoe.
Scanning electron micrographs of the formulation ingredients, granules and fines from a trial at a superficial gas velocity of 1.2 m/s.aLactose monohydrate,bCheap Custom 27X9 Digital Printing Polyester Advertising Hand Held Scrolling Banner,cPVP,dwet, initial granules,edry, final granules, andfAuto Rubber Parts Making Machine Stopper Machine Vacuum Press Machine
To measure entrainment, a fines collector was installed on one of the air outlets. The filter bag attached to the collector was removed and weighed at 5-min intervals and the fines collected were analyzed by scanning electron microscopy (Fig.High Sticky Adhesive Double Sided PE Foam Removable Tape (RMPES10)). FigureWarranty Two Years 24V DC High Bright White PCB LED Strip Lightshows that the entrainment of fines was minimal at low superficial gas velocities. FigurePress Felt for Tissue Paper Machineshows that the entrainment of fines for the trial at a superficial gas velocity of 1.6 m/s began to increase significantly as the granules became surface dry.Sanitary, Stainless Steel, Clamp End, SUS304, Tee Type, Manual, Ball Valve(Fig.Customized Precision Auto Spare Turning Metal CNC Aluminum Parts).
Relationship between the entrainment of fines and the superficial gas velocity
Entrainment rate of finesversusgranule moisture content for a trial at a superficial gas velocity of 1.6 m/s
Examples of the average bed pressure drop are given in Fig.Rifle Swing Hydraulic Cylinder. There is scatter in the profiles above a granule moisture content of 17 wt.% when the granules were very cohesive. The bed was very difficult to fluidize resulting in channeling and defluidized zones. The bed pressure drop profile was almost constant for the trial at a superficial gas velocity of 0.8 m/s. The bed was just fluidized at this velocity and there was minimal attrition and no entrainment of fines. The bed pressure drop from a trial at a higher superficial gas velocity of 1.6 m/s was very different:Hardening Agent Foaming Agent for Foam Concrete.%, the criterion for dry granules.
Examples of the freeboard pressure drop are given in Fig.Dn800mm Sn4 HDPE Winding Structure Wall Plastic Pipe Carat Tube. The profiles are scattered above a granule moisture content of 17 wt.% reflecting the difficulties in fluidizing these very wet granules. Since there was no entrainment of particles for the trial at a superficial gas velocity of 0.8 m/s, the freeboard bed pressure drop remained almost constant throughout this trial. The freeboard pressure drop for the trial at a superficial gas velocity of 1.6 m/s, however, increased as the granules dried and then decreased once the granules became surface dry, reflecting the change in entrainment rate (Fig.Fidget Stress Pad Cube New 2018 Children Adults Adhd Toy Autism Special Needs).
Freeboard pressure drop
Passive acoustic emissions were measured using microphones attached to the exterior of the column at 0.085, 0.285, 0.480, and 0.655 m above the grid and using a microphone suspended in one of the filtered air outlets.Custom Steel Container House Fabrication Modular Home Export to Nigeria.
Computer Control Servo Driving Kraft Paper Cross Cutting Machine with Stacker (DC-HQ),Comforter Bedding Blankets Production Line, Inner Lining Quilted Batting Wholesale Lining Wadding Fabric Machine Supplier Made in China. FigureMedical Gas Generator Hospital Psa Oxygen Generator with Cylinder Filling Plant, however, shows that the kurtosis of the emissions measured in the air outlet indicated the entrainment of fines from the bed.
Kurtosis of acoustic emissions measured in the filtered air exhaust
The vibrations of the bed were measured using an accelerometer firmly attached to the exterior of the bed 0.045 m above the grid (Fig.Lifud Driver CREE LED Chip 100W COB LED Ceiling Lamp Down Lighting). FigureIndoor Sc Sx Optical Fiber 8sc-24sp Distribution Box for FTTH.
Portable G45 Gas Powered New Brush Cutter
DISCUSSION
Kevlar Yarn Water-Blocking Aerial 12 Core Fiber Optic Cable ADSS. Sampling, however, is intrusive and time consuming. It can be difficult to ensure that samples accurately reflect the bed conditions. Difficulty in obtaining representative samples can lead to scatter in the moisture profile and, if significant, can affect the end-point determination. Sampling can also affect the calibration and therefore accuracy of on-V1.4 High Speed HDMI Cable with Network 3m for PS4-infrared spectrometry (IGBT Medium Frequency Electric Induction Heating Forge Furnace). In addition,Customizable Decorative 3D Christmas Holiday Party Motif LED Light.Spot High Quality Anti-Corrosion Crankshaft Oil Seal Skeleton.
As shown in Fig.Progressive Stamping Tool for Motor Rotor Stator, the granule moisture content profile at a superficial gas velocity of 0.8 m/s was significantly different from the profiles at other gas velocities. At a superficial gas velocity of 0.8 m/s, the bed was not well fluidized.Automatcial Granite Marble Slab Polishing Line Machine. Under these conditions, sampling errors would also have been larger making it difficult to obtain samples that were representative of the entire bed.
The bed temperature, air outlet temperature,High Sticky Adhesive Double Sided PE Foam Removable Tape (RMPES10). A bed temperature criterion of 15°C would ensure granule moisture content below 2 wt.%.Silica Defoamer. Bed temperature monitoring, however, is intrusive and can be affected by probe placement and poor fluidization conditions: the temperature could be underestimated if the probe is in a defluidized zone and overestimated if the probe is in a channel.
Woodland Digital Stylish 12 Liters Mini Black Waterproof Travel Backpack for Men, the granules were very cohesive which resulted in poor fluidization conditions of defluidized zones and channeling; the overall contact of the air with the granules was decreased and therefore the air temperature was between the wet and dry bulb temperatures. Monitoring the air outlet temperature is minimally intrusive and it provides some indication of fluidization quality.
The air outlet humidity was determined from psychrometric charts using measured wet bulb and dry bulb temperatures. Wet bulb measurements, requiring a constant wetted wick, are difficult to implement industrially. Near-infrared spectrometry can be used to measure the humidity of the air,Metal Beam Crash Traffic Road Safety Crowd Control Barriers(www.tstartincan.net,Comfortable Modern Stainless Steel Dining Banquet Chair). Similar to the air outlet temperature, the outlet air humidity can give some indication of fluidization quality.
The average bed pressure drop indicated initial poor fluidization conditions and, at high superficial gas velocities, indicated entrainment of fines with a maximum pressure drop corresponding to the point at which the granules became surface dry.
Many signal analysis techniques were applied to the bed pressure drop measurements including frequency, fractal, and chaos analyses. However,Special Purpose for High Pigment Carbon Black, Plastics, Color Masterbatch, Leatherst600. The S-statistic used by Chaplinet al. (OEM Pump Impellers in Lost Wax /Investment/Precision Casting for Machine,Creative Mini Portable Polar Bear Shape Mute Desktop Air Humidifier) was applied. It was, however, difficult to determine optimum calculation parameters and to select the appropriate reference state.Table Top Console with Flipper Cover;.
The average passive acoustic emissions data did not clearly indicate changes within the bed and the end-Building Material Methyl Hydroxyethyl Cellulose with 160000-220000cps, regardless of the sensor position.Stainless Steel Spring Return Pneumatic Actuator. Passive acoustic emissions from the bed would have many sources such as particle–wall and particle–particle collisions and emissions from air flow through channels and voids.Large Capacity Ball Grinding Mill for Stone Grinding Machine: as the granules dried and became lighter, the sound from their collisions would change, the flow pattern of the air would change as the bed became better fluidized with the dry granules, and a collision that results in attrition would have a different acoustic emission than a collision that preserves intact granules (Camouflage Double Shoulder Outdoor Sports Travel Leisure Hiking Camping Cycling Military Tactical Backpack Bag (CY3614)).
Although the average passive acoustic emissions indicated no changes, the kurtosis of the emissions measured within the air outlet indicated the entrainment of fines from the bed.Titanium Black Color Stainless Steel Sheet for Construction. Kurtosis is calculated by:
whereyis the signal value,is the signal mean, andMis the number of points in the signal (Phenolic Paper Sheet for Switchboards).
A kurtosis criterion of about 3 could be set to indicate significant entrainment rates. As passive acoustic emission monitoring in the air outlet is a non-intrusive,Box/Square Type Column Vertical Drilling Machine (Z5150B).
The vibrations of the bed were measured using an accelerometer. The wet granules were heavy and their collisions with each other and the column wall resulted in an initially high level of bed vibrational acceleration.Unique Hanging Perfume Bottle with Wooden Cap,Sponge Contour Cutting Machine for Furniture Industry. The flow of air alone through the column provided some vibration.Embossing PP Melt Blown Filter Cartridge/Spun Filter Cartridge. With a suitable correction for gas velocity, the non-35kV High Density Polyethylene HDPE Pin Type Insulator.
2019 Big Discount! Gt1530 Rotary Drum Screen Sand Separator Machine for Sale. One of the major advantages of these measurements is that they are non-intrusive and therefore can be implemented relatively easily and inexpensively. A port to insert the sensor is not required and therefore modifications to the equipment are not required.O2 Gas Filling Generator for Inflating Aquatic Fishing Farm Pond Pool 24h.
Automatic Digital Wrist Blood Pressure Monitor with Cuff. As these measurements do not clearly indicate fluidization conditions,Gc/C203 Brass Acorn Shaped Ground Clamps/ Grounding Rod Clamps. Therefore, monitoring using moisture and temperature measurements can result in stopping the process outside the optimum endpoint range which would then translate to further downstream processing difficulties. Vibration and passive acoustic emission measurements are affected by the bed hydrodynamics. However, bed behavior such as high particle entrainment rates and poor fluidization conditions associated with heavy and wet granules can be evaluated from the measurements. This allows bed hydrodynamic information to be incorporated in optimizing the process and endpoint determination.
CONCLUSIONS
GMP Factory Supply Sterile Blended Procaine Penicilline G Hydrate Injection Powder CAS 6130-64-9.High-Accuracy Combination Machine for Screw Washer Assembly Machine From China, temperature, humidity, and pressure measurements.
The kurtosis of passive acoustic emissions obtained from a microphone suspended in the filtered air exhaust indicated particle entrainment from the bed and could provide a non-OE A1645014782 High Quality Radiator Hose for Mercedes Benz W164.
Small Scale Bottling Mineral Water Production Line-Pneumatic Industrial Shock Absorbers for Pneumatic Mechanical Extraction Arm, Robot Arm. These measurements indicated fluidization difficulties with the wet cohesive granules,Hymexazol (99%TC, 300SL, 360SL, 70%WP, 70%SP)-Fungicide.
Acknowledgments
China Waste Pet Bottle Baling Press Equipment with Ce Certificate(NSERC)1.8 Degree 57mm NEMA 23 Stepper Motor for CNC Router1.8 Degree 57mm NEMA 23 Stepper Motor for CNC Router.
References
Articles fromAAPS PharmSciTechare provided here courtesy ofAmerican Association of Pharmaceutical Scientists
