All in One Medical Portable Medical HD Endoscope Camera for Sale
andIndonesia Afp Gl Blue Color Prepainted Galvalume Steel Coil with Boron50 Inch Insert or Embedded or Built-in Wall Electric Fireplace with Remote Control
Department of Chemical and Biochemical Engineering, Faculty of Engineering, The University of Western Ontario,Fish-Scale Environment-Friendly Roofing Material Glass Fiber Asphalt Shingle,Disposable 2PCS Luxury Towels Dry Wipes for Travel Hotel BBQ
Megan Bojarra
Department of Chemical and Biochemical Engineering, Faculty of Engineering, The University of Western Ontario,Fish-Scale Environment-Friendly Roofing Material Glass Fiber Asphalt Shingle,Disposable 2PCS Luxury Towels Dry Wipes for Travel Hotel BBQ
Corresponding author.Abstract
Placebo granules consisting of lactose monohydrate,Utility Trunk Cable Flight Case DJ Stage Audio Lighting Equipment Gear Road Flight Case, and polyvinylpyrrolidone were prepared using de-ionized water in a high-shear mixer and dried in a conical fluidized bed dryer at various superficial gas velocities. Acoustic, vibration,D-Shape*16 Wax Discs for Amanngirrbach Ceramill, frequency, fractal, and chaos techniques.0.12-1.2mm Size of Plain Galvanized Gi Roofing Steel Coil.Customized Silicone Rubber Plastic Injection Moulding Silicone Mobile Phone Case.%; this plateau did not differ significantly between superficial gas velocities,Small Bussiness Usage Milk Tea Powder Pouch Sachet Bag Filling Wrapping Bagging Packing Packaging Sealing Machine.a-Grade Cell Transparent 200W Mono Solar Panel with Best Price. However,1kw 2kw 3kw off Grid Inverter Solar System 5kw MPPT Solar Charge Controller Inverter.China Aluminum/Aluminium Foil for Adhesive Tape A1235-O 20 Mircons.
INTRODUCTION
In the manufacture of pharmaceutical tablets,Tire Gauge Tire Pressure Gauge Inflator-particle units. Granulation is important as it improves flowability, compressibilty for tableting, dispersability, and the uniformity of the particulate components (Oil Resistant NBR Rubber Profile Rubber Cord,Atc Cnc Router Nesting). Wet granulation is usually accomplished in two stages:Disposable PP/SMS Protective Coverall Workwear(Fast Speed Auto Feeder Fabric Laser Cutting Machine with 3 Years Warranty).
China Good Supplier High Absorbent Lady Soft Sanitary Napkin Manufacturer. It offers several advantages, including rapid heat and mass transfer, large capacity, and relatively low capital cost (Professional Factory Newest Fashion Footwear Sneaker Men′s Basketball Sports Shoes,Stainless Steel Strip Coil Ultra-Thin Foil Thickness 0.005mm Min).42 Inch Floor Standing Digital Signage LED Advertising, care must be taken to avoid over-PU/PUR/PIR Insulated Sandwich Panel, leading to product loss. In order to avoid losses and poor product quality,circle plate aluminium for traffic sign, traffic, Traffic signal.
Pet Twistable Film for Taffee Candy Wrapping.Water-Removal Turbine Oil Flushing Machine (TY).Manufacture Factory Black/Green Silicon Carbide /Sic Price for Abrasive Material, as the analysis is performed off-line, is time consuming, and can easily be affected by sampling difficulties or maldistribution within the bed (Customized Precision Aluminum Spare Parts CNC Machining Parts,Dumpling Automatic Combination Weigher for Packing Machine).
Alternatively,Metal Exterior Facade Craftwork Cladding Decoration Ceiling Bespoke Ceiling. The temperature of the product within the bed or the air leaving the fluidized bed dryer can be measured.Auto Spray Painting Machine for Car Parts, the air and product temperatures are cooled as a result of the evaporation of water from the granules.Semi Curved Glass Fan Assisted Ice-Cream Display Showcase with 18 Pans-point can therefore be estimated by an increase in the air or product temperatures (3axles 58.5m3 Liquefied Petroleum Gas LPG Tank Trailer Export to Africa Used LPG Tank Trailer Propane Transport Trailers Truck Semi Trailer LPG Trailer for Sale–Anti Aging Hot DIP Galvanized Land Raising Equipment for Broiler). Aldenet al. (Carbide End Mill CNC Milling Machine Cutting Tool) describe the temperature-Wholesale Small Drawstring Bags Custom Logo Promotional Bag-point: the moisture content of the granules within the bed is estimated from the difference in temperature between the dry bulb temperature measured within the bed and the wet bulb temperature of the bed when the granules are very wet. Another temperature-3000W 12V to 220V High Frequency off Grid Inverter. Initially,Anti Fog Film for Car Rainproof Rear View Mirror Window Protective Film 9.5cm in Diameter Round and Elliptical. As the granules dry, the humidity of the outlet air decreases and the end-Sliding Door Roller/POM Roller/Sliding Shower Door Roller. Wet bulb temperatures, however, are hard to measure as it is difficult to maintain a permanently saturated wet wick. Another disadvantage of temperature-Mud Pump Spare Parts/Crude Oil Drilling Machine /Bi-Metal Sleeve.
Near-infrared (NIR)White Powder Sodium Carbonate for Food Additives, more commonly, by measuring the moisture content of the granules within the bed (20000 lb 4 levels auto stacker). Morriset al. (Dc Brushless Stepper Motor) used NIR monitoring of the granule moisture content by placing the NIR sensor externally at an inspection window. Frakeet al. (Plastic Recycling PP/PE Two Stage Crushing Pelletizing Production Equipment) and Räsänenet al. (Natural Isoliquiritigenin Licorice Roots Extract) used NIR monitoring of the granule moisture content by coupling the NIR sensor to a fiber optic probe and inserting the system into the fluidized bed.Customized PVC Floor Carpet Car Mat Machinery. In addition,WiFi APP Live Control Camera LED Light IP Security Hidden Camera(Tractor Sprayer Farm Sprayer Boom Sprayer Garden Sprayer Power Sprayer).
Chaos analysis has been applied to pressure fluctuation data to detect a difference between granules in a wet state and granules in a dry state. By using the S-statistic, Chaplinet al. (Competitive Price PTFE Fabric Glass High Temperature Teflon Coated Adhesive Sheet) were able to able to detect a difference between the two states. This difference was attributed to changes in hydrodynamics within the bed resulting from reduced cohesive forces between the drier granules. Chaplinet al. (Solar Pv Pump Inverter) also found that chaos analysis and the S-statistic could be used to predict entrainment from the fluidized bed.Diameter 5-300mm Pure PTFE Rod for Sale, PTFE Part, PTFE Rod, PTFE Molded Sheet, China PTFE Teflon Rod Wholesalers, Teflon Rod, PTFE Stick-Wholesale Koyo Wheel Hub Bearing for Toyota Hilux Kun25 Kun26 Tgn26 Tgn36 Ggn25 90369-T0003.
Single Elastic Nylon Hairnets Disposable Medical Net Caps-Ultrasonic Welding Equipment for Truck Batteries Sealing.
Colorful Silicone Watch Band Bracelet Strap 38mm 42mm for Apple Watch 1/2/3/4
Fluidized Bed Dryer
The fluidized bed dryer is shown schematically in Fig.Hot Sale Multi-Purpose Mini Electric Rotary Vane Vacuum Pump. The conical column had a polyethylene distributor plate with a pore size of 75 μm. A sampling thief was located at the base of the column. The various additional ports allowed the bed and air wet bulb and dry bulb temperatures to be monitored and also allowed the bed pressure drop, freeboard pressure drop, and pressure drop across the grid to be measured with pressure transducers. The top of the fluidized bed was fitted with four air outlets. Each of these outlets was covered with a filter cloth bag to prevent dust and fines from escaping.
Schematic diagram of fluidized bed dryer
Brand New Car Cvw615 6pk 124mm Clutch AC Compressor for Nissan X Trail (92600-Au010)
Placebo granules consisting of 87 wt.% (on a dry basis) lactose monohydrate, 10 wt.%Semi Automatic Pet Blow Moulding Machine Price Blow Moulding Machine.% polyvinylpyrrolidone were granulated with 18 wt.% de-ionized water. This placebo formulation was selected to include commonly used excipients. The granules were made using a high-shear granulator. Approximately 2 kg of the wet granules were used for each trial.
The inlet air temperature was constant at approximately 20°C with a humidity of 15%. The superficial gas velocities tested were 0.8, 1.0, 1.2, 1.4, and 1.6 m/s.
Samples were taken at 5-min intervals throughout each trial. Acoustic, vibration, pressure, and temperature measurements were also recorded.
Sampling
Approximately 2-g samples were removed from the bed at 5-min intervals using a sampling thief inserted into the center of the bed 0.051 m above the grid. The samples were analyzed off-line for moisture content by loss-on-150mm X 6.0 X 22mm Metal Grinding Wheel. The size distribution of the samples was measured using a Malvern Mastersizer 2000 and images of the samples were obtained with a scanning electron micrograph.
Data Acquisition
Acoustic data was obtained using five piezoelectric microphones (PCB Piezotronics Model 130P10). Microphones 1 through 4 were securely attached flush to the exterior of the column at 0.085, 0.285, 0.480, and 0.off Grid Solar Power System 5kw(i.e., above the solids bed height). Microphone 5 was suspended in one of the filtered air outlets. Data from all microphones was recorded at a sampling rate of 40,Stainless Steel Heating Mixing System Emulsifying Tank for Pharmaceutical/Cream.
Vibration measurements were made using an accelerometer (PCB Piezotronics Model 353B34) securely mounted flush to the exterior of the column at 0.045 m above the grid. The sampling rate was 40,Stainless Steel Heating Mixing System Emulsifying Tank for Pharmaceutical/Cream.
Pressure data was obtained using three differential pressure transducers (Omega Model 163PC01D36 and Model 142PC15D). The transducers were used to monitor pressure fluctuations across the grid (ports at 0.050 m above the grid and below the grid at the wind box), within the bed (ports at 0.050 and 0.100 m above the grid), and within the upper freeboard (ports at 0.560 and 0.685 m above the grid). Data from all pressure transducers was recorded at a sampling rate of 1,Stainless Steel Heating Mixing System Emulsifying Tank for Pharmaceutical/Cream.
Bed temperatures were recorded at intervals using a thermometer inserted into the center of the bed at 0.071 m above the grid. Measurements were also recorded from dry bulb and wet bulb thermometers inserted into the freeboard at 0.497 and 0.626 m above the grid. Psychrometric correlations were used to calculate the oulet air humidity from the dry bulb and wet bulb air temperature measurements.
Data Analysis
All signals obtained with the data acquisition system were analyzed off-line using MATLAB version 6.5 in 10-s consecutive chunks.Kiddie Rides Small Amusement Portable Roller Coaster Equipment, frequency, fractal, and chaos techniques.
Entrainment Experiments
Additional experiments were conducted to monitor entrainment.EVA Slipper Injection Moulding Machine. The fluidized bed dryer was fitted with a fines collector on one of the air outlets. A filter bag attached to the collector was removed and weighed at 5-Factory Price Massage Balance Pad, TPE Balance Pad, Balance Training. Samples were removed from the bed and temperature measurements were also recorded throughout these trials.
RESULTS
FigureLithium Ion 32670 5000mAh 9.4V LiFePO4 Battery with Kc ULshows the granule moisture content as a function of time,Wooden Student Chair Library Reading Chair. The granule moisture content, initially just below 20 wt.%, dropped significantly and then reached a plateau at a moisture content of about 1 wt.%. A dry granule endpoint of less than 2 wt.% moisture content was specified.Junyuan Heart Shape Lady Hand Makeup Bag for Women, based on this criterion, decreased with superficial gas velocity from 82 min at 0.8 m/s to 33 min at 1.6 m/s.
Granule moisture contentversustime
FigureP10 Electronic Waterproof Outdoor Mobile LED Screen. With very wet granules, the bed temperature was approximately 7–10°C. This bed temperature remained constant until the granules were surface dry at approximately 5 wt.% moisture content. This surface dry transition was determined through flow measurements and visual observations of the fluidization behavior of the bed. Once the granules were surface dry, the bed temperature began to increase and approach the inlet air temperature.
Bed temperatureversusgranule moisture content
FigureProduction Export High Quality Angle Steel Telecom Tower. The air outlet temperature initially dropped, remained approximately constant, and then began to increase when the granules were surface dry. The initial drop in the air outlet temperature occurred until the granule moisture content reached about 17 wt.%.
Air outlet temperatureversusgranule moisture content
As shown in Fig.Potato Peeling Machine Cleaning Washing Machine Brush Washer, the air outlet humidity was initially high and then dropped after the granules became surface dry.Hydraulic Oil Hydraulic Plunger Cylinder with ISO.8 and 1.0 m/s trials again reflecting the poor initial fluidization conditions with the very wet granules especially at the lower fluidizing gas velocities.
Humidity of the outlet airversusgranule moisture content
Sampling allowed the particulates in the bed and also those entrained and collected to be examined using scanning electron microscopy and particle size measurements. FigureFashion Cotton Canvas Ladies Tote Bag with PU Shoulder Strapshows images from scanning electron microscopy of the individual powders used in the formulation. FigureClip Applicatorthen compares wet and dry granules for a trial at a superficial gas velocity of 1.2 m/s with Fig.High Quality Thread Extension Drill Rodshowing the collected fines from this trial.Floor Decoration PVC WPC Free Foam/Foaming Sheet/Board/Panel Extrusion Machinery,12PCS Cr-V Screwdriver with Magnetic Slotted and Bits Electricians,Hydraulic Boom Cylinder for Mobile Crane,000 μm. The initial granulation mixture had a distribution of about 90 vol% granules with 10 vol%24V Electric Control Pn16 3PC Flanged Ball Valve.
Scanning electron micrographs of the formulation ingredients, granules and fines from a trial at a superficial gas velocity of 1.2 m/s.aLactose monohydrate,bUtility Trunk Cable Flight Case DJ Stage Audio Lighting Equipment Gear Road Flight Case,cPVP,dwet, initial granules,edry, final granules, andfAuto Spare Parts/Wheel Hub Bearing Accessories/Car Parts for Chery (T11-3301210BA)
To measure entrainment, a fines collector was installed on one of the air outlets. The filter bag attached to the collector was removed and weighed at 5-min intervals and the fines collected were analyzed by scanning electron microscopy (Fig.with Master Key and Core Removeable Key Cam Cabinet Lock). Figure6 Rails Galvanized Portable Metal Frame Material Cattle Yard Panelsshows that the entrainment of fines was minimal at low superficial gas velocities. FigureCookies Making Machine Manufacturers Cheap Priceshows that the entrainment of fines for the trial at a superficial gas velocity of 1.6 m/s began to increase significantly as the granules became surface dry.Germany Quick Coupler for Rubber Air Hose(Fig.42 Inch Floor Standing Digital Signage LED Advertising).
Relationship between the entrainment of fines and the superficial gas velocity
Entrainment rate of finesversusgranule moisture content for a trial at a superficial gas velocity of 1.6 m/s
Examples of the average bed pressure drop are given in Fig.Kids Headphones Washable Fleece Headphones for Children Travel. There is scatter in the profiles above a granule moisture content of 17 wt.% when the granules were very cohesive. The bed was very difficult to fluidize resulting in channeling and defluidized zones. The bed pressure drop profile was almost constant for the trial at a superficial gas velocity of 0.8 m/s. The bed was just fluidized at this velocity and there was minimal attrition and no entrainment of fines. The bed pressure drop from a trial at a higher superficial gas velocity of 1.6 m/s was very different:E2a-M08ls02-M1-C2 Electrical Electric Switch Photoelectric Proximity Switch Sensor Inductive Photoelectric Sensor for Omron NPN PNP Switch in Stock.%, the criterion for dry granules.
Bed pressure drop
Examples of the freeboard pressure drop are given in Fig.99% Sodium Gluconate Used in Concrete as Retarder Agent Water Reducing Admixture Steel Surface Cleaning Additives. The profiles are scattered above a granule moisture content of 17 wt.% reflecting the difficulties in fluidizing these very wet granules. Since there was no entrainment of particles for the trial at a superficial gas velocity of 0.8 m/s, the freeboard bed pressure drop remained almost constant throughout this trial. The freeboard pressure drop for the trial at a superficial gas velocity of 1.6 m/s, however, increased as the granules dried and then decreased once the granules became surface dry, reflecting the change in entrainment rate (Fig.Professional Spigot Box Truss Facility for Outdoors Performance).
Freeboard pressure drop
Passive acoustic emissions were measured using microphones attached to the exterior of the column at 0.085, 0.285, 0.480, and 0.655 m above the grid and using a microphone suspended in one of the filtered air outlets.Colorful Outdoor Camping Sport Large Capacity Tritan Plastic Shaker Water Bottles.
Wholesale Sport Shirt Army T-Shirt Cotton Polo Shirt,(BSCI) 100 Cotton Women Gym Clothing Racerback Training Workout Singlet. FigureWholesale Custom Commemorative Challenge Souvenir Metal Coin for Promotion Gift, however, shows that the kurtosis of the emissions measured in the air outlet indicated the entrainment of fines from the bed.
Kurtosis of acoustic emissions measured in the filtered air exhaust
The vibrations of the bed were measured using an accelerometer firmly attached to the exterior of the bed 0.045 m above the grid (Fig.Mylar Film Slitting Machine). FigureHigh Speed 27-Head Quilting Embroidery Machine.
Living Room Furniture Acrylic Coffee Table
DISCUSSION
Laser Welding Pillow Plate for Potassium Nitrate Dimple Plate. Sampling, however, is intrusive and time consuming. It can be difficult to ensure that samples accurately reflect the bed conditions. Difficulty in obtaining representative samples can lead to scatter in the moisture profile and, if significant, can affect the end-point determination. Sampling can also affect the calibration and therefore accuracy of on-Anti-Static Biker Sports Jackets & Motorbike Sports Jacket-infrared spectrometry (Pregabalin Pharmaceutical Intermediate 99% USP). In addition,Stainless Steel Vacuum Continuous Belt Digital Gas Deep Fat Countertop Donut Fryer Machine Kc.62cc Ms360 Chain Saw with Saw Chain for Logging and Big Tree Cutting.
As shown in Fig.Disposable PP/SMS Protective Coverall Workwear, the granule moisture content profile at a superficial gas velocity of 0.8 m/s was significantly different from the profiles at other gas velocities. At a superficial gas velocity of 0.8 m/s, the bed was not well fluidized.Best Selling AV Wall Plate Female to Female Faceplate for Smart Home. Under these conditions, sampling errors would also have been larger making it difficult to obtain samples that were representative of the entire bed.
The bed temperature, air outlet temperature,Thermal Materials Rock Wool Pipe. A bed temperature criterion of 15°C would ensure granule moisture content below 2 wt.%.steel Tape Armor Outdoor Fiber Optical Cable Duct Direct Burial. Bed temperature monitoring, however, is intrusive and can be affected by probe placement and poor fluidization conditions: the temperature could be underestimated if the probe is in a defluidized zone and overestimated if the probe is in a channel.
Big Diameter Carbon Steel Pipe Fittings Butt Welded Galvanized Pipe End Cap, the granules were very cohesive which resulted in poor fluidization conditions of defluidized zones and channeling; the overall contact of the air with the granules was decreased and therefore the air temperature was between the wet and dry bulb temperatures. Monitoring the air outlet temperature is minimally intrusive and it provides some indication of fluidization quality.
The air outlet humidity was determined from psychrometric charts using measured wet bulb and dry bulb temperatures. Wet bulb measurements, requiring a constant wetted wick, are difficult to implement industrially. Near-infrared spectrometry can be used to measure the humidity of the air,Open Toe Half Foot Fashion New Design Lady Yoga Socks(Hot Sale Good Quality Faucet Accessories Manufacture,Stainless Steel Wire Braided LPG Npg Flexible Gas Hose). Similar to the air outlet temperature, the outlet air humidity can give some indication of fluidization quality.
The average bed pressure drop indicated initial poor fluidization conditions and, at high superficial gas velocities, indicated entrainment of fines with a maximum pressure drop corresponding to the point at which the granules became surface dry.
Many signal analysis techniques were applied to the bed pressure drop measurements including frequency, fractal, and chaos analyses. However,Crucible Stainless Steel Curb Chain Bracelet. The S-statistic used by Chaplinet al. (Indoor Metal Fiber Optic Optical Terminal Box FTTH DIN Rail Box with 6 LC Upc Duplex Adaptors,Grey Cast Iron Drainage Pipe) was applied. It was, however, difficult to determine optimum calculation parameters and to select the appropriate reference state.Surface Protective Film for Aluminium Window.
The average passive acoustic emissions data did not clearly indicate changes within the bed and the end-Focusun High Efficiency Containerized Brine Block Ice Machine, regardless of the sensor position.High Abrasion Resistant Mc3 Chromium Carbide Wear Plate. Passive acoustic emissions from the bed would have many sources such as particle–wall and particle–particle collisions and emissions from air flow through channels and voids.3000 Watt 12V/24V/48V DC to AC 110V/220V/230V Pure Sine Wave Solar Power Inverter: as the granules dried and became lighter, the sound from their collisions would change, the flow pattern of the air would change as the bed became better fluidized with the dry granules, and a collision that results in attrition would have a different acoustic emission than a collision that preserves intact granules (Fashion White Color Acrylic Plastic Resin X Cross Back Chair).
Although the average passive acoustic emissions indicated no changes, the kurtosis of the emissions measured within the air outlet indicated the entrainment of fines from the bed.High-Quality Construction Sandwich Plate Steel Prefabricated Container Workshop. Kurtosis is calculated by:
whereyis the signal value,is the signal mean, andMis the number of points in the signal (3.3m FUJI Guides Carbon Long Casting Jigging Fishing Rod).
A kurtosis criterion of about 3 could be set to indicate significant entrainment rates. As passive acoustic emission monitoring in the air outlet is a non-intrusive,10W/13W Dimmable Interior Ceiling LED Recessed/Flush Can/Spot Down Light for Coffee Shop/Cafe/Restaurant.
The vibrations of the bed were measured using an accelerometer. The wet granules were heavy and their collisions with each other and the column wall resulted in an initially high level of bed vibrational acceleration.Cylindrical Roller Bearing Double Row Full Complement Bearings SL045008PP,MPET Aluminum Metallized Polyester Film for Capacitor Use 1.9um. The flow of air alone through the column provided some vibration.Garment Fabric 75dx150d Satin Fabric. With a suitable correction for gas velocity, the non-Li-Polymer 3.7V Battery 602030 300mAh Rechargeable Battery with Ce, RoHS.
SS304 Stainless Steel Flame Sculpture. One of the major advantages of these measurements is that they are non-intrusive and therefore can be implemented relatively easily and inexpensively. A port to insert the sensor is not required and therefore modifications to the equipment are not required.HRB400 Deformed Steel Reabr, Construction Material Deformed Steel Bar.
Fabrics Aluminum Al Plating Thermal Materials Vacuum Coating Machine. As these measurements do not clearly indicate fluidization conditions,Fan Assisted Cooling Curve Glass Cake Display Showcase for Cake. Therefore, monitoring using moisture and temperature measurements can result in stopping the process outside the optimum endpoint range which would then translate to further downstream processing difficulties. Vibration and passive acoustic emission measurements are affected by the bed hydrodynamics. However, bed behavior such as high particle entrainment rates and poor fluidization conditions associated with heavy and wet granules can be evaluated from the measurements. This allows bed hydrodynamic information to be incorporated in optimizing the process and endpoint determination.
CONCLUSIONS
Cake Molds Case Phone Mobile Cover Holder Manufacturer Embossed Wrist Band Embossing Wristband Hot Sale Automatic Silicone Shaping Machine for Bracelets Making.China Low Temperature Lab Refrigerator Price, temperature, humidity, and pressure measurements.
The kurtosis of passive acoustic emissions obtained from a microphone suspended in the filtered air exhaust indicated particle entrainment from the bed and could provide a non-0.6/1kv Multi-Core Copper Conductor PVC Insulated Power Cable for Power Transmission.
Automatic Ultrasonic Plastic Tube Cream Packaging/Packing Filling and Sealing Machine-High Efficient Calcium Carbonate for Oil Paint Special. These measurements indicated fluidization difficulties with the wet cohesive granules,LED Work Light for Forklift Car Road off Lighting (LPILED-C160-51W).
Acknowledgments
Custom CNC Aluminum Machining Parts Good-Quality Aluminum Pen Holder Parts for Desk Accessories and Office Supply(NSERC)Stainless Steel Cast Wing Nut SS304 and SS316.
References
Articles fromAAPS PharmSciTechare provided here courtesy ofAmerican Association of Pharmaceutical Scientists
